Results 61 to 70 of about 5,550,181 (311)

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Environmental DNA surveys can determine in-stream dominance of non-native brook charr Salvelinus fontinalis over native brown trout Salmo trutta

Ecological Indicators
For effective management of established potentially invasive species it is important to find management target sites (e.g. for depletion or eradication measures). In Sweden, the brook charr is non-native and competes with the native brown trout.
Andreas Broman, William F. Englund, Niclas Gyllenstrand, Joacim Näslund   +3 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

The Impact of Self-Reported Ethnicity Versus Genetic Ancestry on Phenotypic Characteristics of Polycystic Ovary Syndrome (PCOS)

, 2014
Context: It is well established that ethnicity is associated with the phenotype of polycystic ovary syndrome (PCOS). Self-reported ethnicity was shown to be an inaccurate proxy for ethnic origin in other disease traits, and it remains unclear how in PCOS
Lao Grueso, Oscar, Louwers, Yvonne, Laven, Joop, Louwers, Yvonne; id_orcid, Kayser, Manfred, Fauser, BCJM (Bart)   +5 more
core   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Diversity and Distribution of Deep-Sea Fishes off the Emperor Seamounts, Northwestern Pacific Ocean, with DNA Barcodes, Phylogenetic, and Biogeographic Considerations

Journal of Marine Science and Engineering
The results of the trawl survey of the research vessel Professor Kaganovsky over four seamounts (Annei, Jingu, Ojin, and Koko) of the Emperor Seamount Chain in 2019 are presented.
Artem M. Prokofiev, Olga R. Emelianova, Svetlana Y. Saveleva, Alexei M. Orlov   +3 more
doaj   +1 more source

Identification of genetic heterogeneity in Refsum's disease [PDF]

European Journal of Human Genetics, 2000
Refsum's disease (MIM 266500) is a recessive disorder characterised by defective peroxisomal alpha-oxidation of phytanic acid. A Refsum's disease gene, phytanoyl-CoA hydroxylase (PAHX), has been localised to chromosome 10p13 between the markers D10S226-D10S223.
Wierzbicki, A S, Mitchell, J, Lambert-Hammill, M, Hancock, M, Greenwood, J, Sidey, M C, de Belleroche, J, Gibberd, F B   +7 more
openaire   +3 more sources

Genetic characterization of the Makrani people of Pakistan from mitochondrial DNA control-region data

, 2015
To estimate genetic and forensic parameters, the entire mitochondrial DNA control region of 100 unrelated Makrani individuals (males, n = 96; females, n = 4) living in Pakistan (Turbat, Panjgur, Awaran, Kharan, Nasirabad, Gwadar, Buleda, Karachi and ...
Rakha, A, Ali, A, Tariq, MA, Ahmad, J, Abbas, G, Akhtar, T, Masooma, S, Oven, Mannis, Hayat, S, Khan, FM, Siddiqi, MH, Haider, N   +11 more
core   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Body fluid identification using a targeted mRNA massively parallel sequencing approach : results of a EUROFORGEN/EDNAP collaborative exercise [PDF]

, 2018
In a previous study we presented an assay for targeted mRNA sequencing for the identification of human body fluids, optimised for the Illumina MiSeq/FGx MPS platform. This assay, together with an additional in-house designed assay for the Ion Torrent PGM/
Hanssen, E. N., K.J. van der Gaag, Morling, N., Porto, M. J., Porto, M J, T.E. Gross, Vidaki, A., Giangasparo, F., C.R. Steffen, F. Giangasparo, D. Syndercombe-Court, Hanssen, E N, E. Pośpiech, Morling, N, Syndercombe-Court, D, Laurent, F-X, Gettings, KB, Hanson, E., Roeder, AD, J. Ballantyne, Gettings, K. B., Mosquera-Miguel, A., Pośpiech, Ewelina, van der Gaag, K J, van den Berge, M, Kayser, M., A. Vidaki, Laurent, FX, Dorum, G, Parson, W., Hanssen, E.N., Hanson, E, M. Trautmann, Gross, T E, Steffen, C R, C. Xavier, Laurent, F.-X., Hansen, S, Kampmann, M-L, Roeder, A.D., Kayser, M, Johann, KS, Schulze Johann, K., Porto, MJ, Berti, A, P. Brito, M. Kayser, E. Hanson, Steffen, C. R., Phillips, C., C. Haas, Ingold, S, Elsmore, P, Schneider, P M, Xavier, C, Gettings, K.B., Mosquera-Miguel, A, Xavier, C., Vannier, J, Berti, A., W. Parson, Branicki, W., van den Gaag, K.J., M.J. Porto, Kayser, Manfred, Vidaki, A, Phillips, C, Roeder, A D, Dørum, G., Hanssen, EN, M. van den Berge, Ballantyne, J, W. Branicki, Schneider, PM, Steffen, CR, Elsmore, P., Ballantyne, J., E.N. Hanssen, N. Morling, Parson, W, A.D. Roeder, S. Ingold, S. Hansen, van der Gaag, KJ, Gross, T.E., Kampmann, M.-L., F.-X. Laurent, Schulze Johann, K, Verdoliva, V, G. Dørum, Vidaki, Athina, A. Berti, Giangasparo, F.; id_orcid, Giangasparo, F, M.-L. Kampmann, Schneider, P.M., Vannier, J., Gross, TE, Haas, C, A. Mosquera-Miguel, K. Schulze Johann, Dørum, G, Steffen, C.R., van den Berge, M., Verdoliva, V., Gettings, K B, Hansen, S., Haas, C., Pośpiech, E., Gross, T. E., Syndercombe-Court, D., P. Elsmore, Pośpiech, E, Kampmann, ML, Branicki, W, C. Phillips, Trautmann, M., J. Vannier, Roeder, A. D., Porto, M.J., P.M. Schneider, Vidaki, Athina; id_orcid, Berge, M, Johann, K.Schulze, V. Verdoliva, Branicki, Wojciech, Trautmann, M, Ingold, S., K.B. Gettings, Schneider, P. M., van der Gaag, K. J., Brito, P., Brito, P   +132 more
core   +1 more source