Results 81 to 90 of about 7,102,789 (361)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

MicroRNA markers for forensic body fluid identification obtained from microarray screening and quantitative RT-PCR confirmation [PDF]

, 2010
MicroRNAs (miRNAs) are non-protein coding molecules with important regulatory functions; many have tissue-specific expression patterns. Their very small size in principle makes them less prone to degradation processes, unlike messenger RNAs (mRNAs ...
Choi, Ying, Wiemer, Erik, van Kuijk, Patricia, Boersma, Ton, Wiemer, Erik; id_orcid, Kayser, Manfred, Zubakov, Dmitry   +6 more
core   +1 more source

The production of arabitol by a novel plant yeast isolate Candida parapsilosis 27RL-4

Open Life Sciences, 2017
Polyalcohol arabitol can be used in the food and pharmaceutical industries as a natural sweetener, a dental caries reducer, and texturing agent. Environmental samples were screened to isolate effective yeast producers of arabitol.
Kordowska-Wiater Monika, Kuzdraliński Adam, Czernecki Tomasz, Targoński Zdzisław, Frąc Magdalena, Oszust Karolina   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Identification and characterization of novel rapidly mutating Y-chromosomal short tandem repeat markers [PDF]

, 2020
Short tandem repeat polymorphisms on the male‐specific part of the human Y‐chromosome (Y‐STRs) are valuable tools in many areas of human genetics. Although their paternal inheritance and moderate mutation rate (~10−3 mutations per marker per meiosis ...
Henke, Juergen, Henke, Lotte, Winkler, Christian, Lubach, Delano, Ploski, R, Lessig, R. (Rüdiger), Lubach, DN (Delano), Dobosz, T, Ralf, A. (Arwin), Larmuseau, Maarten H.D., Larmuseau, M.H.D. (Maarten), Kayser, M.H. (Manfred), Ploski, Rafal, Kousouri, N., Roewer, L. (Lutz), Dobosz, Tadeusz, Schulz, I., Lessig, Ruediger, Winkler, C, Purps, J, Henke, J, Henke, L, Purps, Josephine, Lubach, D., Schulz, Iris, Roewer, L, Ralf, Arwin, Roewer, Lutz, Dobosz, T. (Tadeusz), Lessig, R, Henke, J. (Jürgen), Krajewski, P, Schulz, I, Larmuseau, MHD, Ploski, R. (Rafal), Kousouri, Nefeli, Winkler, C., Krajewski, Pawel, Kayser, Manfred   +38 more
core   +1 more source

Genetic identification of an expansive mechanoreceptor sensitive to skin stroking

Cell, 2015
Summary Touch perception begins with activation of low-threshold mechanoreceptors (LTMRs) in the periphery. LTMR terminals exhibit tremendous morphological heterogeneity that specifies their mechanical receptivity. In a survey of mammalian skin, we found
Ling Bai, Ling Bai, Brendan P. Lehnert, Junwei Liu, Nicole L. Neubarth, Travis L. Dickendesher, Pann H. Nwe, Colleen Cassidy, C. Woodbury, D. Ginty   +9 more
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A Digital Technique for Online Identification and Tracking of Power System Harmonics Based on Real Coded Genetic Algorithm [PDF]

, 2006
Current and voltage waveforms of a distribution or a transmission system are not pure sinusoids. There are distortions in these waveforms that consist of a combination of the fundamental frequency, harmonics and high frequency transients.
Zamanan, N., Sykulski, J.K., Al-Othman, A.K.   +2 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease

Circulation Research, 2017
Rationale: Coronary artery disease (CAD) is a complex phenotype driven by genetic and environmental factors. Ninety-seven genetic risk loci have been identified to date, but the identification of additional susceptibility loci might be important to ...
P. van der Harst, N. Verweij
semanticscholar   +1 more source