Results 41 to 50 of about 5,357,131 (305)

Characterization of novel loci controlling seed oil content in Brassica napus by marker metabolite-based multi-omics analysis

Genome Biology, 2023
Background Seed oil content is an important agronomic trait of Brassica napus (B. napus), and metabolites are considered as the bridge between genotype and phenotype for physical traits.
Long Li, Zhitao Tian, Jie Chen, Zengdong Tan, Yuting Zhang, Hu Zhao, Xiaowei Wu, Xuan Yao, Weiwei Wen, Wei Chen, Liang Guo   +10 more
doaj   +1 more source

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

API-Constrained Genetic Improvement [PDF]

, 2016
ACGI respects the Application Programming Interface whilst using genetic programming to optimise the implementation of the API. It reduces the scope for improvement but it may smooth the path to GI acceptance because the programmer’s code remains unaffected; only library code is modified.
William B. Langdon, David Robert White, Mark Harman, Yue Jia 0001, Justyna Petke   +4 more
openaire   +1 more source

Rethinking Genetic Improvement Programming [PDF]

Proceedings of the Companion Publication of the 2015 Annual Conference on Genetic and Evolutionary Computation, 2015
We re-examine the central motivation behind Genetic Improvement\ud Programming (GIP), and argue that the most\ud important insight is the concept of applying Genetic Programming\ud to existing software. This viewpoint allows us to\ud make several observations about potential directions for GIP\ud research.
David Robert White, Jeremy Singer
openaire   +2 more sources

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Trait ontology analysis based on association mapping studies bridges the gap between crop genomics and Phenomics

BMC Genomics, 2019
Background Trait ontology (TO) analysis is a powerful system for functional annotation and enrichment analysis of genes. However, given the complexity of the molecular mechanisms underlying phenomes, only a few hundred gene-to-TO relationships in plants ...
Qingchun Pan, Junfeng Wei, Feng Guo, Suiyong Huang, Yong Gong, Hao Liu, Jianxiao Liu, Lin Li   +7 more
doaj   +1 more source

Diurnal RNAPII-tethered chromatin interactions are associated with rhythmic gene expression in rice

Genome Biology, 2022
Background The daily cycling of plant physiological processes is speculated to arise from the coordinated rhythms of gene expression. However, the dynamics of diurnal 3D genome architecture and their potential functions underlying the rhythmic gene ...
Li Deng, Baibai Gao, Lun Zhao, Ying Zhang, Qing Zhang, Minrong Guo, Yongqing Yang, Shuangqi Wang, Liang Xie, Hao Lou, Meng Ma, Wei Zhang, Zhilin Cao, Qinghua Zhang, C. Robertson McClung, Guoliang Li, Xingwang Li   +16 more
doaj   +1 more source

Synthetic Benchmarks for Genetic Improvement [PDF]

Proceedings of the IEEE/ACM 42nd International Conference on Software Engineering Workshops, 2020
Genetic improvement (GI) uses automated search to find improved versions of existing software. If over the years the potential of many GI approaches have been demonstrated, the intrinsic cost of evaluating real-world software makes comparing these approaches in large-scale meta-analyses very expensive.
Aymeric Blot, Justyna Petke
openaire   +3 more sources

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source