Results 181 to 190 of about 3,634,544 (343)

(259) A Genetic Linkage Map and a cDNA Library for Watermelon [PDF]

open access: gold, 2005
Amnon Levi   +10 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Polycystic liver disease is genetically heterogeneous: clinical and linkage studies in eight Finnish families [PDF]

open access: bronze, 2002
Pia Tahvanainen   +5 more
openalex   +1 more source

PLINK: a tool set for whole-genome association and population-based linkage analyses.

open access: yesAmerican Journal of Human Genetics, 2007
S. Purcell   +10 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

High-resolution genetic linkage map of European pear (Pyrus communis) and QTL fine-mapping of vegetative budbreak time [PDF]

open access: gold, 2018
Gilad Gabay   +6 more
openalex   +1 more source

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