Results 51 to 60 of about 4,905,945 (358)

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Psoriasis and Psoriatic Arthritis—Associated Genes, Cytokines, and Human Leukocyte Antigens

Medicina
In recent years, research has intensified in exploring the genetic basis of psoriasis (PsO) and psoriatic arthritis (PsA). Genome-wide association studies (GWASs), including tools like ImmunoChip, have significantly deepened our understanding of disease ...
Marek Zalesak, Lubos Danisovic, Stefan Harsanyi   +2 more
doaj   +1 more source

Identification of Novel Genetic Markers of Breast Cancer Survival

Journal of the National Cancer Institute, 2015
Background: Survival after a diagnosis of breast cancer varies considerably between patients, and some of this variation may be because of germline genetic variation.
Qi Guo, M. Schmidt, P. Kraft, S. Canisius, Constance Chen, Sofia Khan, J. Tyrer, M. Bolla, Qin Wang, J. Dennis, K. Michailidou, M. Lush, S. Kar, J. Beesley, A. Dunning, M. Shah, K. Czene, Hatef Darabi, M. Eriksson, D. Lambrechts, C. Weltens, K. Leunen, S. Bojesen, B. Nordestgaard, S. F. Nielsen, H. Flyger, J. Chang-Claude, A. Rudolph, P. Seibold, D. Flesch-Janys, C. Blomqvist, K. Aittomäki, R. Fagerholm, T. Muranen, F. Couch, J. Olson, C. Vachon, I. Andrulis, J. Knight, G. Glendon, A. Mulligan, A. Broeks, F. Hogervorst, C. Haiman, B. Henderson, F. Schumacher, L. Le Marchand, J. Hopper, H. Tsimiklis, C. Apicella, M. Southey, A. Cox, S. Cross, M. Reed, G. Giles, R. Milne, C. Mclean, R. Winqvist, K. Pylkäs, A. Jukkola-Vuorinen, Mervi Grip, M. Hooning, A. Hollestelle, J. Martens, A. V. D. van den Ouweland, F. Marmé, A. Schneeweiss, Rongxi Yang, B. Burwinkel, J. Figueroa, S. Chanock, J. Lissowska, E. Sawyer, I. Tomlinson, M. Kerin, N. Miller, H. Brenner, A. K. Dieffenbach, V. Arndt, B. Holleczek, A. Mannermaa, V. Kataja, V. Kosma, Jaana M. Hartikainen, Jingmei Li, Judith S. Brand, K. Humphreys, P. Devilee, R. Tollenaar, C. Seynaeve, P. Radice, P. Peterlongo, B. Bonanni, P. Mariani, P. Fasching, M. Beckmann, A. Hein, A. Ekici, G. Chenevix-Trench, Rosemary L. Balleine, K. Phillips, J. Benítez, M. P. Zamora, J. A. Arias Perez, P. Menéndez, A. Jakubowska, J. Lubiński, Katarzyna Jaworska–Bieniek, K. Durda, U. Hamann, M. Kabisch, H. Ulmer, T. Rüdiger, S. Margolin, V. Kristensen, Silje Nord, D. Evans, J. Abraham, Helena M Earl, L. Hiller, J. Dunn, S. Bowden, C. Berg, D. Campa, W. Diver, S. Gapstur, M. Gaudet, S. Hankinson, R. Hoover, A. Hüsing, R. Kaaks, M. Machiela, W. Willett, Myrto Barrdahl, F. Canzian, S. Chin, C. Caldas, D. Hunter, S. Lindstrom, M. García-Closas, P. Hall, D. Easton, D. Eccles, N. Rahman, H. Nevanlinna, P. Pharoah   +145 more
semanticscholar   +1 more source

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Molecular diagnosis of visceral leishmaniasis from blood samples using different genetic markers: A simple, sensitive and less invasive diagnostic approach

Practical Laboratory Medicine
Visceral leishmaniasis (VL), or kala-azar, is a deadly disease with high fatality rates if diagnosis and treatment are delayed. Diagnosis is often delayed due to symptoms that mimic other conditions.
Harish Kumar Shah, K.R. Rajesh, P.A. Fathima, R.S. Aiswarya, P.M. Ajithlal, Prasanta Saini   +5 more
doaj   +1 more source

Analysis of the genetic diversity of Dragon fruit based on ISSR markers in Colombia

Brazilian Journal of Biology, 2022
Selenicereus megalanthus H. is a tropical fruit belonging to the family Cactaceae, is rich in essential nutrients, antioxidants and bioactive components. It presents wide variability in different characteristics and a great demand in the market; however,
A. C. Morillo, M. S. Mora, Y. Morillo
doaj   +1 more source

Exploring Diallelic Genetic Markers: The HardyWeinberg Package

, 2015
Testing genetic markers for Hardy-Weinberg equilibrium is an important issue in genetic association studies. The HardyWeinberg package offers the classical tests for equilibrium, functions for power computation and for the simulation of marker data under
J. Graffelman
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

ANÁLISIS DE LA DIVERSIDAD GENÉTICA DE LA MORA (Rubus spp.) EN EL DEPARTAMENTO DE BOYACÁ

Biotecnología en el Sector Agropecuario y Agroindustrial, 2016
A simple of 21 Rubus spp genetic ecotypes were characterized using markers Random Microsatellite RAMs. The seven primers produced a total of 160 polymorphic bands with molecular weights between 350 and 1500 Kb.
MÓNICA YADIRA DOTOR ROBAYO, LEONARDO ARIEL GONZÁLEZ MENDOZA, MAYERLY ALEJANDRA CASTRO, ANA CRUZ MORILLO CORONADO, YACENIA MORILLO CORONADO   +4 more
doaj   +1 more source

Characterization of the individual capacity for repair of genotoxic damage of a Bulgarian hESC line and two commonly used stabilized cell lines

Biotechnology & Biotechnological Equipment, 2022
The number of stem cell lines worldwide grows steadily, including disease-specific lines and lines derived from specific tissues. The proportion of stem cell lines that were established in strictly xeno-free conditions is rapidly increasing, but it is ...
Rumena Petkova, Pavlina Chelenkova, Borislav Arabadjiev, Roumen Pankov, Stoyan Chakarov   +4 more
doaj   +1 more source