Results 91 to 100 of about 945,949 (268)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Genetic parameters for earnings in Quarter Horse

open access: yesGenetics and Molecular Research, 2014
In this study, we estimated the heritability (h(2)) of earnings in the Quarter Horse in order to evaluate the inclusion of this trait in breeding programs. Records from 14,754 races of 2443 horses from 1978-2009 were provided by Sorocaba Hippodrome, São Paulo, Brazil.
Silva, A. P. A.   +3 more
openaire   +5 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Effect of heat stress on semen characteristics and genetics in Thai native grandparent roosters

open access: yesPoultry Science
: Grandparent roosters are crucial in poultry breeding programs and significantly influence future bird generations' genetic makeup and performance. However, these roosters face considerable challenges from heat stress, which can adversely affect their ...
Jiraporn Juiputta   +3 more
doaj   +1 more source

Determination of the Body Condition Score and Its Relationship with Milk Yield in Turkish Holstein Cows

open access: yesJournal of Agricultural Sciences, 2017
It is quite important to keep the condition of cows under surveillance due to conduct of nutritional programs in dairy herds as well as genetic relations with other traits.
Aşkın Galiç
doaj   +1 more source

On the Optimization of Visualizations of Complex Phenomena [PDF]

open access: yes, 2005
The problem of perceptually optimizing complex visualizations is a difficult one, involving perceptual as well as aesthetic issues. In our experience, controlled experiments are quite limited in their ability to uncover interrelationships among ...
Bair, Althea D   +2 more
core   +2 more sources

Variability in genetic parameters among small populations

open access: yesGenetical Research, 1977
SUMMARYFor a model in which quantitative traits are assumed to be determined solely by additive genes at many loci, formulae are developed for the variance among replicated small populations of sizeN, maintained without selection, of the additive genetic variance, heritability, genetic correlations and similar parameters. The base population is assumed
P J, Avery, W G, Hill
openaire   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Estimation of genetic parameters and comparison of random regression animal and sire models of production traits in the first three lactations of Iranian Holsteins [PDF]

open access: yesBiotechnology in Animal Husbandry, 2014
This study was conducted to compare of random regression (RR) animal and sire models for estimation of the genetic parameters for production traits of Iranian Holstein dairy cows.
Mohammadi A., Alijani S.
doaj  

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