Genetic Predisposition to SARS-CoV-2 Infection: Cytokine Polymorphism and Disease Transmission within Households [PDF]
Biology, 2023 We addressed the question of the influence of the molecular polymorphism of cytokines from different T helper subsets on the susceptibility to SARS-CoV-2 infection. From a cohort of 527 samples (collected from 26 May 2020 to 31 March 2022), we focused on
Marius Saal +4 more
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Genome-wide analysis of genetic predisposition to Alzheimer’s disease and related sex disparities [PDF]
Alzheimer’s Research & Therapy, 2019 Background Alzheimer’s disease (AD) is the most common cause of dementia in the elderly and the sixth leading cause of death in the United States. AD is mainly considered a complex disorder with polygenic inheritance.
Alireza Nazarian +2 more
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Genetic markers of children asthma: predisposition to disease course variants
Вавиловский журнал генетики и селекции, 2023 Asthma is a heterogeneous and often difficult to treat condition that results in a disproportionate cost to healthcare systems. Children with severe asthma are at increased risk for adverse outcomes including medication-related side effects, life ...
M. V. Smolnikova +3 more
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The effect of type 2 diabetes genetic predisposition on non-cardiovascular comorbidities [PDF]
Nature CommunicationsType 2 diabetes is associated with a range of non-cardiovascular non-oncologic comorbidities. To move beyond associations and evaluate causal effects between type 2 diabetes genetic predisposition and 21 comorbidities, we apply Mendelian randomization ...
Ana Luiza Arruda +18 more
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PLoS ONE, 2009 Background and aimsMeningococcal disease remains one of the most important infectious causes of death in industrialized countries. The highly diverse clinical presentation and prognosis of Neisseria meningitidis infections are the result of complex host ...
Antonio Salas +5 more
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Genetic clues for predisposition to severe disease [PDF]
Nature Reviews Immunology, 2021 Alexandra Flemming
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Integrating Vascular Aging and Genetic Risk: The Combined Impact of Estimated Pulse Wave Velocity and Genetic Predisposition on Coronary Artery Disease [PDF]
J Am Heart AssocChang Sheng +6 more
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Predisposition to Neuropsychiatric Disease: Common Genetic Risk Factors
Focus, 2018 Victor I. Reus
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Interaction between genetic predisposition to successful ageing and chronic air pollution on lung disease in elderly women: results of the German SALIA cohort [PDF]
BMJ Open Respir ResSara Kress +5 more
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Clinical Pediatric Hematology-Oncology, 2023 Cancer predisposition syndromes (CPS) are a group of genetic disorders that increase the risk of developing various types of cancer. The prevalence of CPS in children has been known to be up to 18-20% based on recent reports.
Jae Won Yoo
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