Results 31 to 40 of about 284,664 (210)

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

The Impact of Diabetes and Metabolic Syndrome Burden on Pain, Neuropathy Severity and Fiber Type

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Determine the association between diabetes and metabolic syndrome (MetS) burden (number of MetS criteria fulfilled) and pain, neuropathy severity, and fiber type involvement in individuals with established polyneuropathy. Methods The Peripheral Neuropathy Research Registry was queried for individuals with type 1 and type 2 diabetes ...
Long Davalos, Brian C. Callaghan, Lavanya Muthukumar, Simone Thomas, Evan L. Reynolds, A. Gordon Smith, J. Robinson Singleton, Ahmet Höke, Senda Ajroud‐Driss, Mazen M. Dimachkie, Stefanie Geisler, David M. Simpson, PNRR Study Group, Amro M. Stino   +13 more
wiley   +1 more source

Military Service Roles and ALS Among Veterans: A Matched Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT While military service is an established risk factor for amyotrophic lateral sclerosis (ALS), it remains unclear whether this association is linked to combat. We conducted a matched case–control study comparing 191 ALS patients who were veterans of the Israeli Defense Forces (IDF) with known military service type and 1910 matched controls. The
Asaf Honig, Roy Dayan, Amir Knaani, Hagai Levine, Marc Gotkine   +4 more
wiley   +1 more source

Associations of clock genes polymorphisms with soft tissue sarcoma susceptibility and prognosis [PDF]

, 2018
BACKGROUND: Dysfunction of the circadian clock and polymorphisms of some circadian genes have been linked to cancer development and progression. We investigated the relationship between circadian genes germline variation and susceptibility or prognosis ...
Benna, Clara, Del Fiore, Paolo, Mocellin, Simone, Rajendran, Senthilkumar, Rossi, Carlo Riccardo, Spiro, Giovanna, Tropea, Saveria   +6 more
core   +2 more sources

Cholesteatoma and family history: An international survey [PDF]

, 2020
Objective To explore the relative frequency of a family history of cholesteatoma in patients with known cholesteatoma, and whether bilateral disease or earlier diagnosis is more likely in those with a family history.
Clark, Allan, Collins, Rachael, Hong Ta, Ngan, Jennings, Barbara A., Philpott, Carl M., Prinsley, Peter, Steel, Nick   +6 more
core   +1 more source

Analysis of the Longitudinal Behavior of Serum Levels of Soluble Flt1 and Placental Growth Factor in Pregnant Patients With Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective This study analyzed longitudinal trajectories of soluble Flt1 (sFlt1) levels, placenta growth factor (PlGF) levels, and sFlt1:PlGF ratios in a cohort of pregnant patients with systemic lupus erythematosus (SLE). Methods Blood samples were collected (14–18, 24–26, 30–32, 34–36, and 38–40 weeks), stored at −80°C, and evaluated for serum levels ...
Nilson R. de Jesús, Guilherme R. de Jesús, Marcela I. Lacerda, Flávia C. dos Santos, Jeane de S Nogueira, Luiz Cristóvão Porto, Evandro S. F. Coutinho, Evandro M. Klumb   +7 more
wiley   +1 more source

Systematic Comparison of Commercial Uranyl‐Alternative Stains for Negative‐ and Positive‐Staining Transmission Electron Microscopy of Organic Specimens

Advanced Healthcare Materials, EarlyView.
Negative‐ and positive‐staining TEM is essential for rapid nanometer‐resolution characterization of organic specimens ranging from nanoparticles to cells. Uranyl salts are widely used negative‐/positive‐stains but are radioactive and highly toxic to users and the environment.
Vera M. Kissling, Stephanie Eitner, Davide Bottone, Gea Cereghetti, Peter Wick   +4 more
wiley   +1 more source

Border Terriers under primary veterinary care in England: demography and disorders [PDF]

, 2017
The Border Terrier is a working terrier type that is generally considered to be a relatively healthy and hardy breed. This study aimed to characterise the demography and common disorders of Border Terriers receiving veterinary care in England using de ...
A Agresti, A Egenvall, A Gough, A Tvarijonaviciute, A-S Lequarré, AJ German, AR Boyko, BA Niemiec, BR Kirkwood, C Dedola, C Gorrel, D O'Neill, DD Sleator, DG O'Neill, DG O'Neill, DG O'Neill, DG O'Neill, DG O'Neill, DG O'Neill, DG O'Neill, DG O'Neill, EM Lund, EM Lund, ER Shore, F Mariani, FC Calboli, FE Taylor-Brown, FS Roedler, GJ Patronek, HF Proschowsky, HG Parker, HG Parker, ID Robertson, J Lipton, J Sampson, J Stavisky, J Summers, JF Summers, K Christensen, L Asher, L Kearsley-Fleet, LJ DeBowes, LM Collins, LM Collins, LT Glickman, LT Glickman, M Demirkiran, M Downes, M Ratsitorahina, MD Willard, MJ Mattin, OV Horst, P Bateson, P D’Aquila, P Sandøe, PC Bartlett, PD McGreevy, PE Holt, R Collins, R Johns, RA Packer, RK Wayne, S Acharya, T Lewis, V Black, VJ Adams, W Low   +66 more
core   +1 more source

Inorganic Dielectric Materials Coupling Micro‐/Nanoarchitectures for State‐of‐the‐Art Biomechanical‐to‐Electrical Energy Conversion Devices

Advanced Materials, EarlyView.
Biomechanical‐to‐electrical energy conversion devices are uniquely suited for self‐driven physiological information monitoring and powering human–computer interaction systems. These devices based on micro‐/nanoarchitectured inorganic dielectric materials (MNIDMs) have shown ultrahigh electromechanical performance and thus great potential for practical ...
Jia‐Han Zhang, Zhengtong Li, Zeng Liu, Mingxuan Li, Jiaxin Guo, Jinhua Du, Changkun Cai, Shaohui Zhang, Ningning Sun, Yong Li, Xingtao Xu, Xihong Hao, Yusuke Yamauchi   +12 more
wiley   +1 more source

Non‐Invasive Diagnosis of Hypertrophic Cardiomyopathy by Breath

Advanced Sensor Research, EarlyView.
The use of sensor technologies for the diagnosis of hypertrophic cardiomyopathy (HCM) by identification of volatile organic compounds (VOCs) in breath samples. By combining gas chromatography‐mass spectrometry (GC‐MS) and electronic nose (eNose) platforms, specific VOC patterns associated with HCM are detected and analyzed.
Yael Hershkovitz‐Pollak, Manhal Habib, Yoav Y. Broza, Olga Katz, Harry Rakowski, Hossam Haick   +5 more
wiley   +1 more source