Results 31 to 40 of about 320,413 (381)

Prevalence and breed predisposition for thoracolumbar intervertebral disc disease in cats [PDF]

open access: yes, 2016
Objectives The objective was to evaluate the prevalence and possible breed predilections for thoracolumbar intervertebral disc disease (IVDD) in cats. Methods Medical records and imaging studies of cats diagnosed with thoracolumbar IVDD between January ...
De Decker, S, Volk, H A, Warner, A-S
core   +1 more source

Genetic predisposition of cholesterol gallstone disease

open access: yesAnnals of Hepatology, 2006
Gallstone disease (GSD) is the result of the interaction between genetic and environmental factors and it is a major disease cause of surgery with high costs to health systems. Worldwide prevalence varies according to the ethnic population suggesting that high prevalence of GSD in certain ethnic groups is due to the presence of genetic factors ...
Arturo Panduro   +4 more
openaire   +4 more sources

Sleep characteristics modify the association between genetic predisposition to obesity and anthropometric measurements in 119,679 UK Biobank participants [PDF]

open access: yes, 2017
Background - Obesity is a multifactorial condition influenced by genetics, lifestyle and environment. Objective - To investigate whether the association between a validated genetic profile risk score for obesity (GPRS-obesity) with body mass index (BMI)
Bailey, Mark E.S.   +10 more
core   +1 more source

Genomics knowledge and attitudes among European public health professionals. Results of a cross-sectional survey [PDF]

open access: yes, 2020
Background The international public health (PH) community is debating the opportunity to incorporate genomic technologies into PH practice. A survey was conducted to assess attitudes of the European Public Health Association (EUPHA) members towards their
Baccolini, V.   +10 more
core   +2 more sources

Risk of newly developed atrial fibrillation by alcohol consumption differs according to genetic predisposition to alcohol metabolism: a large-scale cohort study with UK Biobank

open access: yesBMC Medicine, 2023
Background The predictive relationship between mild-to-moderate alcohol consumption and the risk of incident atrial fibrillation (AF) remains controversial.
Chan Soon Park   +9 more
doaj   +1 more source

Genetic Predisposition and Inflammatory Bowel Disease [PDF]

open access: yesGastroenterology Research, 2013
Published reports demonstrated finding of different susceptible mutant alleles in association with inflammatory bowel disease (CD/UC) in diseased individuals from different populations. It was then assumed that the existence of different associated mutant alleles in subjects with inflammatory bowel disease from different populations means different ...
openaire   +3 more sources

Missense mutations in the perforin (PRF1) gene as a cause of hereditary cancer predisposition [PDF]

open access: yes, 2016
Perforin, a pore-forming toxin released from secretory granules of NK cells and CTLs, is essential for their cytotoxic activity against infected or cancerous target cells.
Chaudhry, MS   +7 more
core   +1 more source

A continuum of psychosis, one human gene, and not much else - the case for homogeneity [PDF]

open access: yes, 1995
The contention of this paper is that psychoses are not a collection of separate and unrelated diseases, but a set of diverse expressions of a single underlying entity.
Crow, Prof TJ
core   +1 more source

Glutathione S-transferase T1 and M1 polymorphisms and risk of thyroid neoplasms [PDF]

open access: yesArchive of Oncology, 2003
Background: In order to test the possibility of association between GSTT1 and M1 (glutathione S-transferase) null allele variant, in which the entire gene is absent, and the risk of TCO (thyroid carcinoma with cell oxyphilia), the case-control study was ...
Stankov Karmen   +3 more
doaj   +1 more source

Genetic predisposition and the variable course of infectious diseases

open access: yesDeutsches Ärzteblatt international, 2022
Contact with a pathogen is followed by variable courses of infectious disease, which are only partly explicable by classical risk factors. The susceptibility to infection is variable, as is the course of disease after infection. In this review, we discuss the extent to which this variation is due to genetic factors of the affected individual (the host).
Axel, Schmidt   +4 more
openaire   +2 more sources

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