Prevalence and breed predisposition for thoracolumbar intervertebral disc disease in cats [PDF]
Objectives The objective was to evaluate the prevalence and possible breed predilections for thoracolumbar intervertebral disc disease (IVDD) in cats. Methods Medical records and imaging studies of cats diagnosed with thoracolumbar IVDD between January ...
De Decker, S, Volk, H A, Warner, A-S
core +1 more source
Genetic predisposition of cholesterol gallstone disease
Gallstone disease (GSD) is the result of the interaction between genetic and environmental factors and it is a major disease cause of surgery with high costs to health systems. Worldwide prevalence varies according to the ethnic population suggesting that high prevalence of GSD in certain ethnic groups is due to the presence of genetic factors ...
Arturo Panduro+4 more
openaire +4 more sources
Sleep characteristics modify the association between genetic predisposition to obesity and anthropometric measurements in 119,679 UK Biobank participants [PDF]
Background - Obesity is a multifactorial condition influenced by genetics, lifestyle and environment. Objective - To investigate whether the association between a validated genetic profile risk score for obesity (GPRS-obesity) with body mass index (BMI)
Bailey, Mark E.S.+10 more
core +1 more source
Genomics knowledge and attitudes among European public health professionals. Results of a cross-sectional survey [PDF]
Background The international public health (PH) community is debating the opportunity to incorporate genomic technologies into PH practice. A survey was conducted to assess attitudes of the European Public Health Association (EUPHA) members towards their
Baccolini, V.+10 more
core +2 more sources
Background The predictive relationship between mild-to-moderate alcohol consumption and the risk of incident atrial fibrillation (AF) remains controversial.
Chan Soon Park+9 more
doaj +1 more source
Genetic Predisposition and Inflammatory Bowel Disease [PDF]
Published reports demonstrated finding of different susceptible mutant alleles in association with inflammatory bowel disease (CD/UC) in diseased individuals from different populations. It was then assumed that the existence of different associated mutant alleles in subjects with inflammatory bowel disease from different populations means different ...
openaire +3 more sources
Missense mutations in the perforin (PRF1) gene as a cause of hereditary cancer predisposition [PDF]
Perforin, a pore-forming toxin released from secretory granules of NK cells and CTLs, is essential for their cytotoxic activity against infected or cancerous target cells.
Chaudhry, MS+7 more
core +1 more source
A continuum of psychosis, one human gene, and not much else - the case for homogeneity [PDF]
The contention of this paper is that psychoses are not a collection of separate and unrelated diseases, but a set of diverse expressions of a single underlying entity.
Crow, Prof TJ
core +1 more source
Glutathione S-transferase T1 and M1 polymorphisms and risk of thyroid neoplasms [PDF]
Background: In order to test the possibility of association between GSTT1 and M1 (glutathione S-transferase) null allele variant, in which the entire gene is absent, and the risk of TCO (thyroid carcinoma with cell oxyphilia), the case-control study was ...
Stankov Karmen+3 more
doaj +1 more source
Genetic predisposition and the variable course of infectious diseases
Contact with a pathogen is followed by variable courses of infectious disease, which are only partly explicable by classical risk factors. The susceptibility to infection is variable, as is the course of disease after infection. In this review, we discuss the extent to which this variation is due to genetic factors of the affected individual (the host).
Axel, Schmidt+4 more
openaire +2 more sources