Results 181 to 190 of about 1,850,896 (312)

Potential Targets for CRISPR/Cas Knockdowns to Enhance Genetic Resistance Against Some Diseases in Wheat (Triticum aestivum L.). [PDF]

Front Genet, 2022
Taj M, Sajjad M, Li M, Yasmeen A, Mubarik MS, Kaniganti S, He C.   +6 more
europepmc   +1 more source

Bacterial Genetics and Drug Resistance [PDF]

Public Health Reports (1896-1970), 1952
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Sheep Genetic Resistance to Gastrointestinal Nematode Infections: Current Insights from Transcriptomics and Other OMICs Technologies-A Review. [PDF]

Pathogens
Sinhalage K, Polizel GHG, Karrow NA, Schenkel FS, Cánovas Á.   +4 more
europepmc   +1 more source

Prediction of Genetic Resistance for Scrapie in Ungenotyped Sheep Using a Linear Animal Model. [PDF]

Genes (Basel), 2021
Boareki M, Schenkel F, Kennedy D, Cánovas A.   +3 more
europepmc   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Honey bee genetic resistance outperforms a cold-storage induced halt in brood production to control mites and viruses. [PDF]

Sci Rep
Meikle WG, Weiss M, Adjaye D, Ricigliano VA.   +3 more
europepmc   +1 more source

Maize Lethal Necrosis disease: review of molecular and genetic resistance mechanisms, socio-economic impacts, and mitigation strategies in sub-Saharan Africa. [PDF]

BMC Plant Biol, 2022
Biswal AK, Alakonya AE, Mottaleb KA, Hearne SJ, Sonder K, Molnar TL, Jones AM, Pixley KV, Prasanna BM.   +8 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Integrating image-based phenotyping and QTL mapping to enhance genetic resistance and accelerate breeding for bacterial grain rot resistance in rice. [PDF]

Theor Appl Genet
Park JR, Lee G, Lee HS, Lee SY, Ha SK, Kang K, Jin M, Suh JP, Seo J, Choi YM, Lee BC, Park HS.   +11 more
europepmc   +1 more source