Results 31 to 40 of about 7,418,451 (334)
Anopheles gambiae Genome Conservation as a Resource for Rational Gene Drive Target Site Selection
Insects, 2021 The increase in molecular tools for the genetic engineering of insect pests and disease vectors, such as Anopheles mosquitoes that transmit malaria, has led to an unprecedented investigation of the genomic landscape of these organisms.
Nace Kranjc +3 more
doaj +1 more source
Ironing out the details: Untangling dietary iron and genetic background in diabetes [PDF]
, 2018 The search for genetic risk factors in type-II diabetes has been hindered by a failure to consider dietary variables. Dietary nutrients impact metabolic disease risk and severity and are essential to maintaining metabolic health.
Lawson, Heather A, Miranda, Mario A
core +2 more sources
Genetic resistance to transmissible spongiform encephalopathies (TSE) in goats
EFSA journal. European Food Safety Authority, 2017 Breeding programmes to promote resistance to classical scrapie, similar to those for sheep in existing transmissible spongiform encephalopathies (TSE) regulations, have not been established in goats. The European Commission requested a scientific opinion
A. Ricci +26 more
semanticscholar +1 more source
Mutations in TAC1B: a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris
mBio, 2020 Candida auris is an emerging multidrug-resistant pathogen of global concern, known to be responsible for outbreaks on six continents and to be commonly resistant to antifungals. While the vast majority of clinical C.
J. Rybak +12 more
semanticscholar +1 more source
Frontiers in Immunology, 2021 Highly pathogenic avian influenza viruses (HPAIVs) cause severe systemic disease and high mortality rates in chickens, leading to a huge economic impact in the poultry sector. However, some chickens are resistant to the disease.
Albert Perlas +12 more
doaj +1 more source
Evolutionary biology and genetic techniques for insect control [PDF]
, 2015 The requirement to develop new techniques for insect control that minimize negative environmental impacts has never been more pressing. Here we discuss population suppression and population replacement technologies. These include sterile insect technique,
Bolton, Michael +2 more
core +1 more source
Genomic comparison of diverse Salmonella serovars isolated from swine. [PDF]
, 2019 Food animals act as a reservoir for many foodborne pathogens. Salmonella enterica is one of the leading pathogens that cause food borne illness in a broad host range including animals and humans.
Barrett, John B +9 more
core +2 more sources
Insulin resistance: Genetic associations with depression and cognition in population based cohorts
Experimental Neurology, 2019 &NA; Insulin resistance, broadly defined as the reduced ability of insulin to exert its biological action, has been associated with depression and cognitive dysfunction in observational studies.
Sophia Frangou +13 more
semanticscholar +1 more source
Cancer Discovery, 2018 CDK4/6 inhibition with endocrine therapy is now a standard of care for advanced estrogen receptor-positive breast cancer. Mechanisms of CDK4/6 inhibitor resistance have been described preclinically, with limited evidence from clinical samples.
B. O’Leary +12 more
semanticscholar +1 more source
Plants, 2020 Using resistant cultivars is a common approach to managing blackleg of canola/rapeseed caused by Leptosphaeria maculans (Lm). Quantitative resistance (QR), as opposed to major-gene resistance, is of interest because it is generally more durable, due to ...
Michelle Hubbard, Chun Zhai, Gary Peng
doaj +1 more source