Results 41 to 50 of about 942,879 (267)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Antimicrobial resistance transmission in the environmental settings through traditional and UV-enabled advanced wastewater treatment plants: a metagenomic insight

Environmental Microbiome
Background Municipal wastewater treatment plants (WWTPs) are pivotal reservoirs for antibiotic-resistance genes (ARGs) and antibiotic-resistant bacteria (ARB).
Absar Talat, Yasir Bashir, Nadeem Khalil, Connor L. Brown, Dinesh Gupta, Asad Ullah Khan   +5 more
doaj   +1 more source

MADS-box BSISTER transcription factors up-regulate proanthocyanidin biosynthesis in grapevine

Horticultural Plant Journal
Proanthocyanidins (PAs) are a group of oligomeric flavonoids also known as condensed tannins. PAs in human diet have antioxidant and health-promoting effects.
Yujin Tang, Ling Wang, Congbo Huang, Ting Zhao, Yan Li, Chaohong Zhang   +5 more
doaj   +1 more source

Research on resistance to sunflower broomrape: an integrated vision

Oilseeds and fats, crops and lipids, 2016
Sunflower broomrape (Orobanche cumana Wallr.) parasitization on sunflower was first observed at the end of the 19th century and has continued since then jeopardizing sunflower cultivation in many areas of Europe and Asia.
Velasco Leonardo, Pérez-Vich Begoña, Fernández-Martínez José M.   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Performance- and Resistance-Related Early Responses of Colombian Elite Rubber Tree Genotypes under Low Pressure of South American Leaf Blight: Implications for Disease Management in the Amazon

Plants, 2023
The cultivation of Hevea brasiliensis, the primary commercial source of natural rubber, is strongly impacted by South American leaf blight (SALB) disease, caused by the fungus Pseudocercospora ulei.
Lyda Constanza Galindo-Rodríguez, Armando Sterling, Herminton Muñoz-Ramirez, Jesica Andrea Fonseca-Restrepo   +3 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

‘Sultanina’ leaves increase their trehalose content in response to grapevine brown leaf spot infection by regulating the pentose and glucuronate interchange pathway

Plant Stress
Since the first discovery of grapevine brown leaf spot disease in Turpan, Xinjiang, China, in 2007, it has been a common occurrence in grapevine-growing regions.
Chuan Zhang, Haixia Zhong, Haoyu Chen, Nuerziya Yalimaimaiti, Ju Liang, Jiachen Duan, Yameng Yang, Songlin Zhang, Vivek Yadav, Xiaoming Zhou, Xinyu Wu, Fuchun Zhang, Jingzhe Hao   +12 more
doaj   +1 more source

Transcript imaging and candidate gene strategy for the characterisation of Prunus/PPV interactions

Plant Protection Science, 2002
Plum pox virus (PPV), the causing agent of the sharka disease, belongs to the genus Potyvirus that contains the largest number of virus species infecting plants. The virus genome has been extensively characterised and sequenced.
V. Decroocq, V. Schurdi-Levraud, D. Wawrzyńczak, J.P. Eyquard, M. Lansac   +4 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source