Results 111 to 120 of about 7,107,321 (247)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

International Plant Genetic Resources Institute (IPGRI): Financial Statements for December 31, 2004 and 2003 with Independent Auditor's Report

, 2005
Independent auditor's report for IPGRI's financial statements as of December 31, 2004 and 2003 and statements of activity, statements of assets, and cash flows.
International Plant Genetic Resources Institute
core  

Morphological and molecular characterization of ‘Saragolla’ wheats (Triticum turgidum subsp. durum from Abruzzo, Italy)

Genetic Resources
A morphological and genetic characterization of autochthonous ‘Saragolla’ wheats, currently cultivated in Abruzzo Region (Italy), was carried out.
Agata Rascio, Vanessa De Simone, Lorenzo Goglia, Silvana Paone, Maria Pellegrino, Giuseppe Sorrentino   +5 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Report of the Fifth Meeting of the CGIAR Genetic Resources Policy Committee

, 1997
Brief summary of the outcome of a workshop on ethics and equity held April 22-25, 1997, in Foz do Iguacu, Brazil, together with a few items from the meeting of the Genetic Resources Policy Committee held immediately afterwards which the GRPC wished to ...
CGIAR Genetic Resources Policy Committee
core   +1 more source

Overview of germplasm collecting activities for plant genetic resources for food and agriculture in Sudan from 2002 to 2022

Genetic Resources
From 2002 to 2022, the Agricultural Plant Genetic Resources Conservation and Research Centre (APGRC) in Sudan conducted 56 collecting missions for plant genetic resources for food and agriculture (PGRFA) in Sudan.
Ibrahim Mohamed El Tahir, Ali Zakaria Babiker, Elsadig Ahmed Abdalla, Awadelkarim Alam Elhuda Ahmed, Mashaer Obaed Yousif Goda, Magdi Ahmed Mohamed Elgabri   +5 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

European genetic resources conservation in a rapidly changing world [PDF]

Even though genetic resources represent a fundamental reservoir of options to achieve sustainable development goals in a changing world, they are overlooked in the policy agenda and severely threatened.
Hintum, Theo J. L. van, Maxted, Nigel, Sharrock, Suzanne, Sturaro, Enrico, Laloë, Denis, Kraigher, Hojka, Lefévre, François, Bou Dagher Kharrat, Magda, Westergren, Marjana, Charvolin-Lemaire, Eléonore, Bojkovski, Danijela, Bozzano, Michele, Hiemstra, Sipke Joost, Van Hintum, Theo, Kharrat, Magda Bou Dagher, Restoux, Gwendal   +15 more
core   +1 more source