Results 101 to 110 of about 7,016,767 (306)

A small-scale assessment of the availability of EURISCO accessions

Genetic Resources
A critical assessment of plant genetic resource (PGR) availability in Europe reveals a significant gap between documented accessions and those that are practically obtainable for researchers and breeders.
Erik Wijnker, Theo van Hintum
doaj   +1 more source

Cryopreservation of eucalyptus genetic resources.

Cryo letters, 2013
The long-term preservation of forest genetic resources is a vital part of preserving our forest crops for future generations. Unfortunately, there are few genebanks dedicated to forest trees and very few methods for long-term preservation of forest genetic resources collections aside from field plantings of a limited number of seed-derived or elite ...
Kaya, E., Alves, A., Rodrigues, L., Jenderek, M., Hernández Ellis, M., Ozudogru, A., Ellis, David   +6 more
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Characterizing genetic diversity within and between native Nordic horse breeds utilizing and comparing the EquCab3.0 and EquCab_Finn reference genomes

Genetic Resources
Sustainable breeding of native breeds is essential to preserve genetic diversity and cultural heritage. Several native Nordic horse breeds are at risk of extinction and lack genetic characterization.
Nathalie Smogeli, Iryna Shutava, Signa Ravnafoss, Maria Kjetså, Juha Kantanen, Kisun Pokharel, Therese Selle, Sofia Mikko, Susanne Eriksson, Peer Berg   +9 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Expanding the genetic diversity of chickpeas from the Ukrainian genebank to new agricultural systems

Genetic Resources
Enhancing crop resilience to abiotic factors in an increasingly unstable climate is a critical challenge, one that can be met by actively using the existing gene pool of the crops.
Nadiia Vus, Olha Bezuhla, Serhiy Sylenko, Antonina Vasylenko, Viacheslav Sichkar, Mykola Kondratenko, Margarita Barylko   +6 more
doaj   +1 more source

Review of Plant Genetic Resources, Utilization and Conservation of Genetic Resources

International Journal of Basic Sciences and Applied Computing
According to the review, genetic resources are derived from native plant landraces and wild species. Material originating from plants is referred to as genetic resources. These genetic resources are very important for nutrition and the development of agricultural productivity.
Bekele Kindie, Tahir Abdala
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Characterization of Iranian rice genetic resources for key grain quality traits

Genetic Resources
Grain quality traits are crucial for rice (Oryza sativa L.) breeding, as they significantly influence consumer preferences and market value. This study evaluated 48 diverse rice genotypes, including a strong representation of Iranian landraces that ...
Mostafa Modarresi
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source