Results 81 to 90 of about 7,107,321 (247)

Brazil's implementation of access and benefit-sharing and the Nagoya Protocol: Analyzing some trends and positions in the ongoing debate

open access: yesGenetic Resources
Access and benefit-sharing (ABS) arising from the utilization of biodiversity’s genetic resources and traditional knowledge is the third objective of the Convention on Biological Diversity (CBD). Since its inception, some parties to the CBD have enacted
Eduardo Relly
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Genetic Resources, Equity and International Law [PDF]

open access: yes, 2009
This thesis examines the application of international law to the uses of agricultural crop plants termed plant genetic resources for food and agriculture.
Guneratne, Camena Erica
core  

Forest genetic resources conservation and management: In plantations and genebanks (ex situ) : Vol. 3

open access: yes, 2019
This guide is the third volume of a series of three that deal with the conservation of forest (trees and shrubs) genetic resources. This volume addresses technical requirements, and some applied approaches and experiences with the ex situ conservation ...
International Plant Genetic Resources Institute
core   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Sorghum genetic resources in Africa

open access: yes, 1980
Meeting: Crop Genetic Resources in Africa, 4-6 Jan.
Gebrekidan, B.
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Memorandum of Understanding between the Indian Council of Agricultural Research and the International Board for Plant Genetic Resources fo Scientific and Technical Cooperation of Plant Genetic Resources [PDF]

open access: yes, 1987
Memorandum of understanding between the Indian Council of Agricultural Research and the IBPGR signed November 23, 1987 in New Delhi, India. MOU establishes scientific and technical cooperation in plant genetic resources.
International Plant Genetic Resources Institute
core   +1 more source

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