Results 91 to 100 of about 10,428,446 (310)

Representation of Sickle Cell Disease Patients in Pediatric and Adult Care: What We Discovered Using Informatics for Integrating Biology and the Bedside (i2b2) Data

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Transitioning from pediatric to adult care is a high‐risk period for individuals with sickle cell disease (SCD). An initial observation at one academic medical center suggested a sex‐based disparity in clinic populations, prompting a national investigation.
Laurie J. Duckworth, Kholod Alhassan, Ada De La Osa, John Stephen, Yue Yao, Diana J. Wilkie   +5 more
wiley   +1 more source

Genetic Structuring and Connectivity of European Squid Populations in the Mediterranean Sea Based on Mitochondrial COI Data

Fishes
Understanding population connectivity and genetic structure is crucial for the effective management of exploited marine species. This study investigates the population genetics of the common European squid (Loligo vulgaris) across the Mediterranean Sea ...
Vasiliki Pertesi, Joanne Sarantopoulou, Athanasios Exadactylos, Dimitrios Vafidis, Georgios A. Gkafas   +4 more
doaj   +1 more source

Characterization of Genetic Diversity in Accessions of Prunus salicina Lindl: Keeping Fruit Flesh Color Ideotype While Adapting to Water Stressed Environments

Agronomy, 2019
The genetic diversity of 14 Japanese plum (Prunus salicina Lindl) landraces adapted to an ecosystem of alternating flooding and dry conditions was characterized using neutral simple sequence repeat (SSR) markers. Twelve SSRs located in six chromosomes of
Cintia V. Acuña, Juan G. Rivas, Silvina M. Brambilla, Teresa Cerrillo, Enrique A. Frusso, Martín N. García, Pamela V. Villalba, Natalia C. Aguirre, Julia V. Sabio y García, María C. Martínez, Esteban H. Hopp, Susana N. Marcucci Poltri   +11 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Genome-Wide SNP Analysis Reveals the Unique Genetic Diversity Represented by Fat-Tailed Coarse-Wooled Sheep Breeds of Kazakhstan

Biology
Background: The fat-tailed coarse-wooled sheep breeds exhibit excellent reproductive performance, exceptional adaptability to pasture conditions, and high precocity, contributing to enhanced meat, fat, and wool productivity in sheep breeding. Despite the
Kairat Dossybayev, Makpal Amandykova, Daniya Ualiyeva, Tilek Kapassuly, Altynay Kozhakhmet, Elena Ciani, Bakytzhan Bekmanov, Rauan Amzeyev   +7 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Isoenzymatic differentiation in putative hybrid swarm population (Pinus mugo Turra x P. sylvestris L.) from "Torfowisko Zieleniec" peat-bog

Acta Societatis Botanicorum Poloniae, 2014
Isoenzyme variability of eight groups of individuals from different parts of putative hybrid swarm population (P. mugo Turra x P. sylvestris L.) from "Torfowisko Zieleniec" peat-bog complex was studied at ten enzymatic loci.
Anna Siedlewska
doaj   +1 more source