Results 101 to 110 of about 2,690,236 (305)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Genotyping by Sequencing of Cultivated Lentil (Lens culinaris Medik.) Highlights Population Structure in the Mediterranean Gene Pool Associated With Geographic Patterns and Phenotypic Variables

Frontiers in Genetics, 2019
Cultivated lentil (Lens culinaris Medik.) is one of the oldest domesticated crops and one of the most important grain legumes worldwide. The Mediterranean Basin holds large part of lentil biodiversity; however, no genetic structure was defined within the
Stefano Pavan, Stefano Pavan, Nicoletta Bardaro, Valentina Fanelli, Angelo Raffaele Marcotrigiano, Giacomo Mangini, Francesca Taranto, Francesca Taranto, Domenico Catalano, Cinzia Montemurro, Claudio De Giovanni, Concetta Lotti, Luigi Ricciardi   +12 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Population genetic structure based on microsatellite markers in rubber tree (Hevea brasiliensis) germplasm collection : [P483] [PDF]

, 2014
Hevea brasiliensis is native to the Amazonian rain forest and an important source of natural rubber. All high-yielding cultivars of rubber tree in the world originated from breeding programs initially developed in Southeast Asia with a very narrow ...
Campos Mantello, Camila, Conson, Andre R.O., Da Silva, Carla Cristina, Garcia, Antonio Augusto Franco, Garcia, Dominique, Le Guen, Vincent, Pereira de Souza, Anete, Souza, Livia Moura   +7 more
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Bumblebees mediate landscape effects on a forest herb's population genetic structure in European agricultural landscapes

Ecology and Evolution
Spatially isolated plant populations in agricultural landscapes exhibit genetic responses not only to habitat fragmentation per se but also to the composition of the landscape matrix between habitat patches.
Jannis Till Feigs, Siyu Huang, Stephanie I. J. Holzhauer, Jörg Brunet, Martin Diekmann, Per‐Ola Hedwall, Katja Kramp, Tobias Naaf   +7 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Size‐Dependent Genetic Erosion due to Human Logging and Conservation Recommendation for an Endangered Yew (Taxus fuana) in Tibet, China

Ecology and Evolution
Taxus fuana, an endemic plant of the West Himalayas, has an extremely small population size and is currently threatened by heavy logging due to its medicinal properties. However, the impacts of human‐induced logging on population size and tree size‐class
Xiao‐Lu Shen‐Tu, Yan Chen, Jun‐Yin Deng, Yao‐Bin Song, Ming Dong   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Synchronization of Coupled Nonidentical Genetic Oscillators

, 2006
The study on the collective dynamics of synchronization among genetic oscillators is essential for the understanding of the rhythmic phenomena of living organisms at both molecular and cellular levels.
Boyd S, Chunguang Li, Goldbeter A, Goldbeter A, Kazuyuki Aihara, Luonan Chen, Smolen P, Vidyasagar M, Winfree A T, Wu C W, Wu C W   +10 more
core   +1 more source