Results 121 to 130 of about 2,690,236 (305)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Genetic variation and population dispersal of Yangtze voles Microtus fortis calamorum in the Dongting Lake region

open access: yesCurrent Zoology, 2012
To understand genetic variation and population dispersal in the Yangtze vole Microtus fortis calamorum distributed in the Dongting Lake region, 144 individuals were collected from six habitat patches.
Zongming GUO, Pengfei SONG, Cong GUO, Zhaobin SONG, Yong WANG, Bo LI, Meiwen ZHANG, Jianghong RAN
doaj  

The origins of white-chinned petrels killed by long-line fisheries off South Africa and New Zealand

open access: yesPolar Research, 2016
The white-chinned petrel (Procellaria aequinoctialis) is the seabird species most frequently killed by fisheries in the Southern Ocean and is listed by the International Union for the Conservation of Nature and Natural Resources as globally vulnerable ...
N.M.S. Mareile Techow   +3 more
doaj   +1 more source

Genetic structuring in fluctuating populations

open access: yesEcological Informatics, 2006
Abstract The effect of genetic drift in spatially distributed dispersal-linked and density-regulated populations is studied in a classical one-locus two-allele system. We analyse emergence of genetic differentiation assuming random drift only, where the noise-like variability is due to demographic stochasticity.
Veijo Kaitala   +2 more
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Patrones geográficos de diferenciación craneofacial entre poblaciones de la región central del país y otras de Argentina: aportes desde la genética del paisaje

open access: yesRevista del Museo de Antropologia, 2008
In this study we analyze the patterns of spatial variation of a population sample from the pre-Hispanicinhabitants of the central territory of Argentina (Córdoba and San Luis provinces) archaeologically known as«Sierras Centrales», and 13 other samples ...
Mariana Fabra
doaj  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Improving Organizations by Replacing the "Mechanical" Model with the "Organic" one [PDF]

open access: yes
Organizations are currently viewed as artificial structures. However, in our opinion, organizations seem to match a biological structure much better. This paper explores this new approach with some interesting conclusions and results: organizations aim ...
George MOLDOVEANU   +2 more
core  

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