Results 121 to 130 of about 10,428,446 (310)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Current Zoology, 2012 To understand genetic variation and population dispersal in the Yangtze vole Microtus fortis calamorum distributed in the Dongting Lake region, 144 individuals were collected from six habitat patches.
Zongming GUO, Pengfei SONG, Cong GUO, Zhaobin SONG, Yong WANG, Bo LI, Meiwen ZHANG, Jianghong RAN
doaj
The origins of white-chinned petrels killed by long-line fisheries off South Africa and New Zealand
Polar Research, 2016 The white-chinned petrel (Procellaria aequinoctialis) is the seabird species most frequently killed by fisheries in the Southern Ocean and is listed by the International Union for the Conservation of Nature and Natural Resources as globally vulnerable ...
N.M.S. Mareile Techow +3 more
doaj +1 more source
The Genetic Structure of Marijuana and Hemp
PLOS ONE, 2015 Despite its cultivation as a source of food, fibre and medicine, and its global status as the most used illicit drug, the genus Cannabis has an inconclusive taxonomic organization and evolutionary history. Drug types of Cannabis (marijuana), which contain high amounts of the psychoactive cannabinoid Δ9-tetrahydrocannabinol (THC), are used for medical ...
Jason Sawler +7 more
openaire +4 more sources
Unexpected Fine-Scale Population Structure in a Broadcast-Spawning Antarctic Marine Mollusc [PDF]
, 2012 Several recent empirical studies have challenged the prevailing dogma that broadcast-spawning species exhibit little or no population genetic structure by documenting genetic discontinuities associated with large-scale oceanographic features.
Peck, Lloyd S. +15 more
core +2 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Revista del Museo de Antropologia, 2008 In this study we analyze the patterns of spatial variation of a population sample from the pre-Hispanicinhabitants of the central territory of Argentina (Córdoba and San Luis provinces) archaeologically known as«Sierras Centrales», and 13 other samples ...
Mariana Fabra
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 2020 Macadamia is an Australian native rainforest tree that has been domesticated and traded internationally for its premium nuts. Common cultivars rely upon a limited gene pool that has exploited only two of the four species.
Thuy Mai +4 more
core +1 more source