Results 111 to 120 of about 10,428,446 (310)

Effect of habitat fragmentationon the genetic structure of the narrow endemic Brongniartia vazquezii [PDF]

open access: yes, 2001
The monoecious, animal-pollinated shrub Brongniartia vazquezii is an endemic and endangered species of the tropical dry forests of Central Mexico. Deforestation of the tropical dry forest has fragmented the habitat and resulted in the isolation of the ...
Jorge González Astorga   +1 more
core  

Genetic population structure of the grass snake (Natrix natrix) in human-altered landscapes in Switzerland [PDF]

open access: yes, 2012
Both the conversion of natural habitats to farmland and efforts at increasing the yield of existing crops contribute to a decline in biodiversity. As a consequence of land conversion, specialised species are restricted to remnants of original habitat ...
Meister, Barbara
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Genetic algorithms for structural editing [PDF]

open access: yes, 1998
This paper describes the use of discrete graphical editing operations to dynamically fit hierarchical structural models to input data. We use the tree adjoining grammar developed by Joshi [l] as a prototypical structural model, and realise the editing process using a genetic algorithm.
Richard Myers, Edwin R. Hancock
openaire   +1 more source

Genetic Structure and Conservation Management of Endemic Salix kusanoi in Fragmented Habitats of Taiwan

open access: yes
Salix kusanoi is an endangered riparian tree species endemic to Taiwan. This study aimed to evaluate the genetic diversity and population structure across eight fragmented populations employing 33 microsatellite loci.
Piumi Chathurika Palangasinghe   +6 more
core   +1 more source

When are pathogen dynamics likely to reflect host population genetic structure?

open access: yes, 2020
Does the structure and connectivity of host populations influence the dynamics and evolution of their pathogens? This topical question is the essence of research investigating the ecology of a Pteropus fruit bat and its zoonotic Nipah virus (NiV ...
Carver, Scott   +3 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The Phytogeographic History of Common Walnut in China

open access: yesFrontiers in Plant Science, 2018
Common walnut (Juglans regia L.) is an economically important hardwood tree species cultivated worldwide for its high quality wood and edible nuts. It is generally accepted that after the last glaciation J.
Xiaojia Feng   +8 more
doaj   +1 more source

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