Results 211 to 220 of about 1,230,887 (337)

THE ACCUMULATION OF GENETIC VARIABILITY IN YEAST

Genetics, 1971
Charles Blatherwick, Christopher Wills
openaire   +3 more sources

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Exploring NEK1 genetic variability in Italian amyotrophic lateral sclerosis patients. [PDF]

J Neurol
Pensato V, Peverelli S, Tiloca C, Magri S, Brusati A, Pingue M, Morelli C, Dalla Bella E, Manini A, Tannorella P, Doretti A, Mandrioli J, Terenghi F, Prelle A, Riva N, Verde F, Eleopra R, Taroni F, Lauria Pinter G, Silani V, Ticozzi N, Gellera C, Ratti A.   +22 more
europepmc   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Genetic Variability of Loci Affecting Meat Quality and Production in Nero Siciliano Pig Breed. [PDF]

Animals (Basel)
Tumino S, Carlentini M, Chessari G, Criscione A, Antoci A, Marletta D, Bordonaro S.   +6 more
europepmc   +1 more source

Estimating genetic divergence and genetic variability with restriction endonucleases. [PDF]

, 1981
William R. Engels
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Cardiac Phenotypes in Fabry Disease: Genetic Variability and Clinical Severity Staging Correlation in a Reference Center Cohort. [PDF]

Genes (Basel)
Faro DC, Di Salvo S, Rodolico MS, Losi V, Capodanno D, Monte IP.   +5 more
europepmc   +1 more source

Genetic Variability within and between Outbred Wistar Strains of Rats

, 1979
Junzo Yamada, Hiroko Nikaido, Sayuri Matsumoto   +2 more
openalex   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source