Results 211 to 220 of about 895,195 (259)
Estimated six per cent loss of genetic variation in wild populations since the industrial revolution
Evolutionary Applications, 2019 Genetic variation is fundamental to population fitness and adaptation to environmental change. Human activities are driving declines in many wild populations and could have similar effects on genetic variation.
Ella Vazquez-Dominguez +2 more
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The American Journal of Medicine, 1963
Abstract The causes of heritable variation in man are mutation and recombination. Further diversity is made possible by the diploid state in which metabolism is influenced by the simultaneous action of homologous genes. Consideration of the events stemming from the action of a single intranuclear gene reveals that the genetic impulse, mediated by a ...
B, CHILDS, W J, YOUNG
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Abstract The causes of heritable variation in man are mutation and recombination. Further diversity is made possible by the diploid state in which metabolism is influenced by the simultaneous action of homologous genes. Consideration of the events stemming from the action of a single intranuclear gene reveals that the genetic impulse, mediated by a ...
B, CHILDS, W J, YOUNG
openaire +2 more sources
American Journal of Primatology, 2004
AbstractThis review summarizes what is currently known concerning genetic variation in gorillas, on both inter‐ and intraspecific levels. Compared to the human species, gorillas, along with the other great apes, possess greater genetic varation as a consequence of a demographic history of rather constant population size. Data and hence conclusions from
Vigilant, L. ; https://orcid.org/0000-0003-4509-1260 +1 more
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AbstractThis review summarizes what is currently known concerning genetic variation in gorillas, on both inter‐ and intraspecific levels. Compared to the human species, gorillas, along with the other great apes, possess greater genetic varation as a consequence of a demographic history of rather constant population size. Data and hence conclusions from
Vigilant, L. ; https://orcid.org/0000-0003-4509-1260 +1 more
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Annual Review of Genetics, 1995
Life span is subject to genetic modification in yeasts, nematodes, fruit flies, mice, humans, and other vertebrates and invertebrates. There are a few single-gene mutants known that extend life span in yeast and nematodes; in other experimental systems the character is treated quantitatively, and generally has a low to moderate heritability.
J W, Curtsinger +6 more
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Life span is subject to genetic modification in yeasts, nematodes, fruit flies, mice, humans, and other vertebrates and invertebrates. There are a few single-gene mutants known that extend life span in yeast and nematodes; in other experimental systems the character is treated quantitatively, and generally has a low to moderate heritability.
J W, Curtsinger +6 more
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Molecular Genetics and Genetic Variation
2010This chapter contains brief notes on molecular genetics, focusing on those aspects most frequently encountered in genetic epidemiology. The main sections cover the organisation and physical structure of genetic material, the mechanisms involved in transmitting genetic material from one generation to the next, and forms of genetic variation.
Mohammed-Elfatih, Twfieg, M Dawn, Teare
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Current Opinion in Plant Biology, 2008
Completion of the genomic sequencing of rice has enhanced the discovery of new genes. Wild rice relatives are good sources for extending the genetic variation of cultivated rice. Reproductive barriers are commonly found in distant crosses of rice and are attracting attention.
Kazuyuki, Doi +2 more
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Completion of the genomic sequencing of rice has enhanced the discovery of new genes. Wild rice relatives are good sources for extending the genetic variation of cultivated rice. Reproductive barriers are commonly found in distant crosses of rice and are attracting attention.
Kazuyuki, Doi +2 more
openaire +2 more sources
Genetic variation and nutrition
Food Reviews International, 1996Advances in genetics and molecular biology indicate that susceptibility to chronic diseases such as coronary artery disease (CAD), hypertension, diabetes, obesity, osteoporosis, alcoholism, cancer, etc., to a great extent is genetically determined. Studies have shown that 50% of the variance in plasma cholesterol concentration is genetically determined,
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Theophylline metabolism: Variation and genetics
Clinical Pharmacology and Therapeutics, 1984Variation of theophylline metabolism in 54 healthy, nonmedicated adults (13 monozygotic [MZ] twin pairs, 11 dizygotic [DZ] twin pairs, and 6 single individuals) was assessed by kinetic study. Elimination rate constant, clearance (Cl), t1/2, and apparent volume of distribution, as well as urine excretion of unchanged theophylline and of the three major ...
Miller, Marvin E. +3 more
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Genetic Variations and Association
2010Publisher Summary This chapter provides information about the human hydroxytryptamine (HT)R6 gene structure, its evolution, and its expression profile in both the brain and in peripheral tissues. The chapter describes the regulatory regions like binding sites for transcription factors (TFs) or for miRNA.
GENNARELLI, Massimo, CATTANEO, Annamaria
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Genetic variation in prehistoric Sardinia
Human Genetics, 2007We sampled teeth from 53 ancient Sardinian (Nuragic) individuals who lived in the Late Bronze Age and Iron Age, between 3,430 and 2,700 years ago. After eliminating the samples that, in preliminary biochemical tests, did not show a high probability to yield reproducible results, we obtained 23 sequences of the mitochondrial DNA control region, which ...
CARAMELLI, DAVID +14 more
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