Results 71 to 80 of about 1,068,124 (306)

Genetic variability for vigor and yield of robusta coffee (Coffea canephora) clones in Ghana

Heliyon, 2022
Effectiveness of plant improvement programs, especially in perennial crops like coffee, may be improved by knowing the level of genetic variation which exist within a breeding population coupled with the knowledge of estimates of genetic parameters for ...
Abraham Akpertey, Esther Anim-Kwapong, Paul Kwasi Krah Adu-Gyamfi, Atta Ofori   +3 more
doaj  

Human Genetic Variation and Parkinson’s Disease [PDF]

Journal of Movement Disorders, 2010
Parkinson’s disease (PD) is a chronic neurodegenerative disorder with multifactorial etiology. In the past decade, the genetic causes of monogenic forms of familial PD have been defined.
Sun Ju Chung
doaj   +1 more source

Molecular Genetic Influences on Normative and Problematic Alcohol Use in a Population-Based Sample of College Students [PDF]

, 2017
Background: Genetic factors impact alcohol use behaviors and these factors may become increasingly evident during emerging adulthood. Examination of the effects of individual variants as well as aggregate genetic variation can clarify mechanisms ...
Adkins, Amy, Aliev, Fazil, Cho, Seung B., Cooke, Megan E., Dick, Danielle M., Edwards, Alexis C., Kendler, Kenneth S., Kitchens, James N., Neale, Zoe, Pedersen, Kimberly, Riley, Brien P., Salvatore, Jessica E., Savage, Jeanne E., Sun, Cuie, Webb, Bradley T., Williamson, Vernell S., Wolen, Aaron R.   +16 more
core   +2 more sources

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

FEBS Letters, EarlyView.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard, Bernadette R. Gochuico, Hadass Pri Chen, Christopher K. E. Bleck, Patricia M. Zerfas, Wendy J. Introne, William A. Gahl, May C. V. Malicdan   +7 more
wiley   +1 more source

Use of Prolamin Polymorphism to Describe Genetic Variation in a Collection of Barley Genetic Resources

Czech Journal of Genetics and Plant Breeding, 2003
The polymorphism of prolamin storage proteins was studied in seed samples of 20 historical cultivars of spring barley (Hordeum vulgare L.) of Czech and Slovak origin, using polyacrylamide gel electrophoresis (PAGE). Only two samples were uniform.
T. Vyhnánek, J. Bednář, S. Helánová, L. Nedomová, J. Milotová   +4 more
doaj   +1 more source

Demographic history and genetic differentiation in apes [PDF]

, 2006
SummaryComparisons of genetic variation between humans and great apes are hampered by the fact that we still know little about the demographics and evolutionary history of the latter species [1–4].
Fischer, A., Nickel, B., Pollack, J., Pääbo, S., Thalmann, O.   +4 more
core   +2 more sources

Cytosolic‐enhanced dark Epac‐based FRET sensors allow for intracellular cAMP detection in live cells via FLIM

FEBS Letters, EarlyView.
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti, Jeffrey B. Klarenbeek, Kees Jalink   +2 more
wiley   +1 more source

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

FEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr, Klaus Mayer, Raffael Schaffrath, Johannes Buchner, Ulrich Brinkmann   +4 more
wiley   +1 more source

Are current ecological restoration practices capturing natural levels of genetic diversity? A New Zealand case study using AFLP and ISSR data from mahoe (Melicytus ramiflorus) [PDF]

, 2015
Sourcing plant species of local provenance (eco-sourcing) has become standard practice in plant community restoration projects. Along with established ecological restoration practices, knowledge of genetic variation in existing and restored forest ...
Clarke, Andrew C., Clarkson, Fiona Marie, Gemmill, Chrissen E.C., Goshorn, Mary, Stevens, Mark I.   +4 more
core   +2 more sources

Bose-Einstein distribution, condensation transition and multiple stationary states in multiloci evolution of diploid population

, 2010
The mapping between genotype and phenotype is encoded in the complex web of epistatic interaction between genetic loci. In this rugged fitness landscape, recombination processes, which tend to increase variation in the population, compete with selection ...
A. Hartmann, C. Darwin, C. J. Pethick, D. Hartl, E. Ben-Naim, Ginestra Bianconi, J. H. Gillespie, J. Hofbauer, J. Monod, J. S. Yedidia, K. Huang, K. Jain, K. Sneppen, L. Peliti, M. A. Nowak, M. Mézard, Olaf Rotzschke, R. A. Fisher, U. Alon   +18 more
core   +1 more source