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Genetic technologies for disease vectors
Current Opinion in Insect Science, 2015The first genetic technologies for insect vectors of disease were introduced 20 years ago. As of today there are 12 classes of genetic technologies used as functional genomic tools for insect vectors of important diseases. Although the applications of genetic technologies in insect disease vectors have been conducted primarily in mosquitoes, other ...
William Reid +2 more
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Genetic and Physical Map of the pLAFR1 Vector
DNA Sequence, 2004This paper presents the complete sequencing and annotation of the pLAFR1 vector. pLAFR is a tetracycline-resistant "cosmid" cloning vector, which is derived from the 20 kb plasmid pRK290, a RK2-derivative. Due to its broad host range, the pLAFR1 vector has been widely used in the genetic analysis of a broad number of gram-negative bacterial species ...
Jozef Vanderleyden +2 more
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Molecular Genetic Manipulation of Mosquito Vectors
Annual Review of Entomology, 1995Despite their central role in disease transmission, relatively little is known of the molecular biology of arthropod vectors. Modern molecular approaches will undoubtedly provide considerable information about gene regulation and expression in vectors and consequently a much better understanding of the biology and molecular biology of vectors.
J. O. Carlson +3 more
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1995
Since the pioneering studies of Edward Jenner on using live virus vaccines during the early 1800s (Baxby 1981), a considerable amount of information has been obtained on the biology and replication of poxviruses. Vaccinia virus, the agent used to vaccinate humans against smallpox and eradicate this disease, has been widely studied in the laboratory due
William I. Cox +2 more
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Since the pioneering studies of Edward Jenner on using live virus vaccines during the early 1800s (Baxby 1981), a considerable amount of information has been obtained on the biology and replication of poxviruses. Vaccinia virus, the agent used to vaccinate humans against smallpox and eradicate this disease, has been widely studied in the laboratory due
William I. Cox +2 more
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Genetics of a Molluscan Vector of Schistosomiasis
Nature, 1970A complex of several genetic factors determines the susceptibility of juvenile Biomphalaria glabratus to infection by Schistosoma mansoni. A simple dominant factor can cause juvenile susceptible snails to become refractory to the parasite at maturity. Stocks of such adults may prove to be of use in genetic control of S. mansoni in endemic areas.
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Vectors for reverse genetics and expression analysis [PDF]
, 2006 The binary Agrobacterium pPZP211 vector is stable and fully sequenced. We have produced derivatives of this vector that can be used for general over-expression, nodule-specific expression, expression pattern analysis, and protein localization studies.
Andersen, Stig Uggerhøj +5 more
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Genetic manipulation of insect vectors as a strategy for the control of vector-borne disease
Annals of Tropical Medicine & Parasitology, 1994A variety of very effective methods have been employed for suppressing insect vector populations, including the application of biological control agents and the elimination of breeding sites, with a continuing and heavy reliance on the use of chemical insecticides.
I P Comley +5 more
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Adenoassociated Virus Vectors for Genetic Immunization
Immunologic Research, 2002Genetic immunization has initiated a new era of vaccine research, which provides a stable and long-lived source of the protein antigen. Such a vaccine is a simple, robust, and effective means of eliciting both antibody- and cell-mediated immune responses compared with protein or peptide vaccines.
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HSV-1 Amplicon Vectors as Genetic Vaccines
2014HSV-1 amplicon vectors have been used as platforms for the generation of genetic vaccines against both DNA and RNA viruses. Mice vaccinated with such vectors encoding structural proteins from both foot-and-mouth disease virus and rotavirus were partially protected from challenge with wild-type virus (D'Antuono et al.
Laimbacher, A S, Fraefel, C
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Herpesviruses as Genetic Vectors
1995The members of the Herpesviridae family are large, DNA-containing, enveloped viruses. Nearly 100 herpesviruses infect a broad spectrum of the animal kingdom (Roizman 1990). So far, seven different types of human herpesviruses have been described (Table 5.1).
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