Results 21 to 30 of about 634,337 (325)
Frontiers in Cellular and Infection Microbiology, 2021 The piRNA pathway is a specialized small RNA interference that in mosquitoes is mechanistically distant from analogous biology in the Drosophila model.
Vanessa M. Macias +5 more
doaj +1 more source
Visualizing genetic constraints [PDF]
, 2013 Principal Components Analysis (PCA) is a common way to study the sources of variation in a high-dimensional data set. Typically, the leading principal components are used to understand the variation in the data or to reduce the dimension of the data for ...
Gaydos, Travis L. +6 more
core +3 more sources
Rescue of splicing-mediated intron loss maximizes expression in lentiviral vectors containing the human ubiquitin C promoter. [PDF]
, 2014 Lentiviral vectors almost universally use heterologous internal promoters to express transgenes. One of the most commonly used promoter fragments is a 1.2-kb sequence from the human ubiquitin C (UBC) gene, encompassing the promoter, some enhancers, first
Cooper, Aaron R +3 more
core +1 more source
Human Vaccines & Immunotherapeutics, 2017 Background: Genetic immunization is expected to induce the expression of antigens in a native form. The encoded peptide epitopes are presented on endogenous MHC molecules, mimicking antigen presentation during a viral infection.
S. Stenler +12 more
doaj +1 more source
Biological Procedures Online, 2003 Disarmed versions of the cytotoxin ricin can deliver fused peptides into target cells leading to MHC class I-restricted antigen presentation [Smith et al. J Immunol 2002; 169:99-107].
Smith Daniel C. +3 more
doaj +1 more source
Insight into the Machinery and Applications for Understanding the Pathogen- Vector Interface [PDF]
, 2012 The availability of genome sequencing data in combination with knowledge of expressed genes via transcriptome and proteome data has greatly advanced our understanding of arthropod vectors of disease.
Barnard, Annette-Christi +4 more
core +1 more source
Antigen capsid-display on human adenovirus 35 via pIX fusion is a potent vaccine platform. [PDF]
PLoS ONE, 2017 Durable protection against complex pathogens is likely to require immunity that comprises both humoral and cellular responses. While heterologous prime-boost regimens based on recombinant, replication-incompetent Adenoviral vectors (AdV) and adjuvanted ...
Nadine C Salisch +10 more
doaj +1 more source
In vivo genetic manipulation of inner ear connexin expression by bovine adeno-Associated viral vectors [PDF]
, 2017 We have previously shown that in vitro transduction with bovine adeno-associated viral (BAAV) vectors restores connexin expression and rescues gap junction coupling in cochlear organotypic cultures from connexin-deficient mice that are models DFNB1 ...
Campioni, Matteo +7 more
core +1 more source
Genetic stereo matching using complex conjugate wavelet pyramids [PDF]
, 2001 A new genetic algorithm-based optimisation technique for stereo matching using complex conjugate wavelet pyramids is proposed. Reliable disparity fields are estimated in the wavelet domain with low computational cost. The new cost function is composed of
Bull, DR +3 more
core +2 more sources
RNA Viral Vectors for Accelerating Plant Synthetic Biology
Frontiers in Plant Science, 2021 The tools of synthetic biology have enormous potential to help us uncover the fundamental mechanisms controlling development and metabolism in plants.
Arjun Khakhar +3 more
doaj +1 more source