Results 61 to 70 of about 4,784,986 (369)
Experimental study on population-based incremental learning algorithms for dynamic optimization problems [PDF]
, 2005 Copyright @ Springer-Verlag 2005.Evolutionary algorithms have been widely used for stationary optimization problems. However, the environments of real world problems are often dynamic. This seriously challenges traditional evolutionary algorithms.
Yang, S, Yao, X
core +2 more sources
Continuous multilinguality with language vectors [PDF]
Conference of the European Chapter of the Association for Computational Linguistics, 2016 Most existing models for multilingual natural language processing (NLP) treat language as a discrete category, and make predictions for either one language or the other. In contrast, we propose using continuous vector representations of language. We show
Robert Östling, J. Tiedemann
semanticscholar +1 more source
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Population-based incremental learning with memory scheme for changing environments [PDF]
, 2005 Copyright @ 2005 ACMIn recent years there has been a growing interest in studying evolutionary algorithms for dynamic optimization problems due to its importance in real world applications.
Yang, S
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
A CRISPR-Cas9 System for Genetic Engineering of Filamentous Fungi
PLoS ONE, 2015 The number of fully sequenced fungal genomes is rapidly increasing. Since genetic tools are poorly developed for most filamentous fungi, it is currently difficult to employ genetic engineering for understanding the biology of these fungi and to fully ...
C. S. Nødvig +3 more
semanticscholar +1 more source
Applications and developments of gene therapy drug delivery systems for genetic diseases
Asian Journal of Pharmaceutical Sciences, 2021 Genetic diseases seriously threaten human health and have always been one of the refractory conditions facing humanity. Currently, gene therapy drugs such as siRNA, shRNA, antisense oligonucleotide, CRISPR/Cas9 system, plasmid DNA and miRNA have shown ...
Xiuhua Pan +6 more
doaj +1 more source
Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes
FEBS Letters, EarlyView.The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji +3 more
wiley +1 more source
Molecular Survey and Genetic Characteristics of Vector-Borne Pathogens in Domestic Dogs from Four Regions of China [PDF]
, 2023 Fangyuan Yin +4 more
openalex +1 more source
Vectors for Glioblastoma Gene Therapy: Viral & Non-Viral Delivery Strategies
Nanomaterials, 2019 Glioblastoma multiforme is the most common and aggressive primary brain tumor. Even with aggressive treatment including surgical resection, radiation, and chemotherapy, patient outcomes remain poor, with five-year survival rates at only 10%.
Breanne Caffery +2 more
semanticscholar +1 more source