Results 111 to 120 of about 8,837 (264)

From lab to law: emerging applications, potential benefits, evolving regulatory framework and challenges for engineered probiotics. [PDF]

Microb Cell Fact
Di Pierro F, Thacharodi A, Kumaraswami M, Suvorov A, Zupet J, Zerbinati N.   +5 more
europepmc   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Safety evaluation of the food enzyme endo-1,4-β-xylanase from the genetically modified <i>Bacillus licheniformis</i> strain NZYM-FX. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Peluso S, Andryszkiewicz M, Liu Y.   +15 more
europepmc   +1 more source

A Systemic Model for Understanding Business Interactions With Biodiversity and Ecosystems

Business Strategy and the Environment, EarlyView.
ABSTRACT Biodiversity loss and ecosystem degradation represent critical threats to human well‐being and economic resilience, challenging businesses to understand and manage their interdependence with natural systems. This study develops a systemic framework—the BioModel—that elucidates the reciprocal relationship between businesses, biodiversity, and ...
Lino Cinquini, Giacomo Pigatto, Andrea Tenucci   +2 more
wiley   +1 more source

Safety evaluation of the food enzyme β-glucosidase from the genetically modified <i>Trichoderma reesei</i> strain DP-Nyk114. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Gomes A, Andryszkiewicz M, Cavanna D, Kovalkovičová N, Liu Y.   +17 more
europepmc   +1 more source

Scalable catalyst production process for oleate hydratase whole‐cell biocatalysis

Biotechnology Progress, EarlyView.
This study establishes a scalable lactose‐induced fed‐batch fermentation for an Escherichia coli whole‐cell biocatalyst containing an oleate hydratase. Operation at a higher growth rate markedly increased biomass yields while maintaining catalyst activity and was demonstrated at 150 L scale.
Rebekka Horstmann, Mario Beckers, Jörn Viell, Fabian Allan Watt, Valentin Steier, Marcel Mann, Jørgen B. Magnus   +6 more
wiley   +1 more source

Safety evaluation of the food enzyme glucan 1,4-α-maltotetraohydrolase from the genetically modified <i>Bacillus licheniformis</i> strain DP-Dzf95. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Cavanna D, Aguilera J, Andryszkiewicz M, Peluso S, Liu Y.   +17 more
europepmc   +1 more source

Improving the Mechanical Properties of Biodegradable Polyhydroxyalkanoates via PHA–PHA Block‐Copolymer Synthesis

Chemistry – A European Journal, EarlyView.
Covalent linkage of a highly crystalline PHBV with a ductile P3HB4HB is shown to produce block copolymers with markedly enhanced extensibility and toughness, outperforming equivalent blends. The results demonstrate that polymer architecture, not composition alone, governs mechanical response, offering a route to biodegradable materials that combine ...
Katrin Blandine Kockler, Paul Lant, Steven Pratt, Bronwyn Laycock   +3 more
wiley   +1 more source

Living Hydrogels: Harnessing Microorganism-Material Synergy for Next-Generation Therapeutics. [PDF]

Adv Sci (Weinh)
Mao S, Bai B, Ye X, Lin Y.
europepmc   +1 more source

Fecal Microbiota Transplantation and Microbiota‐Based Therapeutics in Allogeneic Hematopoietic Stem Cell Transplantation: Current Evidence and Future Directions

Clinical Pharmacology &Therapeutics, EarlyView.
The intestinal microbiome is a key regulator of immune homeostasis, metabolism, and epithelial barrier integrity. In patients with malignant hematological diseases, particularly those undergoing hematopoietic stem cell transplantation, microbiome perturbations by reduced diversity, pathobiont expansion, and loss of beneficial metabolites are common as ...
Bálint Gergely Szabó, Dorina Korózs, Michal Bator, Krisztina Jeszenszky, Viktor Lakatos, László Gopcsa, Péter Reményi, János Sinkó   +7 more
wiley   +1 more source