Results 11 to 20 of about 273,777 (285)

Two new genetically modified mouse alleles labeling distinct phases of retinal ganglion cell development by fluorescent proteins. [PDF]

Dev Dyn, 2020
Ge Y, Wu F, Cheng M, Bard J, Mu X.
europepmc   +3 more sources

Drug-metabolizing enzyme, transporter, and nuclear receptor genetically modified mouse models. [PDF]

Drug Metab Rev, 2011
Jiang XL, Gonzalez FJ, Yu AM.
europepmc   +3 more sources

Ocular surface mucins and local inflammation--studies in genetically modified mouse lines. [PDF]

BMC Ophthalmol, 2015
Shirai K, Saika S.
europepmc   +3 more sources

Adjuvant treatment with tumor-targeting Salmonella typhimurium A1-R reduces recurrence and increases survival after liver metastasis resection in an orthotopic nude mouse model. [PDF]

, 2015
Colon cancer liver metastasis is often the lethal aspect of this disease. Well-isolated metastases are candidates for surgical resection, but recurrence is common. Better adjuvant treatment is therefore needed to reduce or prevent recurrence.
Bouvet, Michael, Chishima, Takashi, Endo, Itaru, Hiroshima, Yukihiko, Hoffman, Robert M, Murakami, Takashi, Tanaka, Kuniya, Zhang, Yong, Zhao, Ming   +8 more
core   +16 more sources

miR-23a/b clusters are not essential for the pathogenesis of osteoarthritis in mouse aging and post-traumatic models

Frontiers in Cell and Developmental Biology, 2023
Osteoarthritis (OA), the most prevalent aging-related joint disease, is characterized by insufficient extracellular matrix synthesis and articular cartilage degradation and is caused by various risk factors including aging and traumatic injury.
Yusuke Fujiwara, Chenyang Ding, Yohei Sanada, Yohei Sanada, Dilimulati Yimiti, Masakazu Ishikawa, Masakazu Ishikawa, Tomoyuki Nakasa, Tomoyuki Nakasa, Naosuke Kamei, Kazunori Imaizumi, Martin K. Lotz, Takayuki Akimoto, Shigeru Miyaki, Shigeru Miyaki, Nobuo Adachi   +15 more
doaj   +1 more source

Genetically modified mouse models for the study of nonalcoholic fatty liver disease. [PDF]

World J Gastroenterol, 2012
Nagarajan P, Mahesh Kumar MJ, Venkatesan R, Majundar SS, Juyal RC.   +4 more
europepmc   +2 more sources

Post-genomic era in agriculture and veterinary science: successful and proposed application of genetic targeting technologies

Frontiers in Veterinary Science, 2023
Gene editing tools have become an indispensable part of research into the fundamental aspects of cell biology. With a vast body of literature having been generated based on next generation sequencing technologies, keeping track of this ever-growing body ...
Ali Mazloum, Maxim Karagyaur, Roman Chernyshev, Antoinette van Schalkwyk, Antoinette van Schalkwyk, Ma Jun, Fu Qiang, Alexander Sprygin   +7 more
doaj   +1 more source

Generation of an immortalized mouse embryonic palatal mesenchyme cell line. [PDF]

PLoS ONE, 2017
Palatogenesis is a complex morphogenetic process, disruptions in which result in highly prevalent birth defects in humans. In recent decades, the use of model systems such as genetically-modified mice, mouse palatal organ cultures and primary mouse ...
Katherine A Fantauzzo, Philippe Soriano
doaj   +1 more source

Animal models for COVID-19: advances, gaps and perspectives

Signal Transduction and Targeted Therapy, 2022
COVID-19, caused by SARS-CoV-2, is the most consequential pandemic of this century. Since the outbreak in late 2019, animal models have been playing crucial roles in aiding the rapid development of vaccines/drugs for prevention and therapy, as well as ...
Changfa Fan, Yong Wu, Xiong Rui, Yuansong Yang, Chen Ling, Susu Liu, Shunan Liu, Youchun Wang   +7 more
doaj   +1 more source

The UCSF Mouse Inventory Database Application, an Open Source Web App for Sharing Mutant Mice Within a Research Community

G3: Genes, Genomes, Genetics, 2020
The UCSF Mouse Inventory Database Application is an open-source Web App that provides information about the mutant alleles, transgenes, and inbred strains maintained by investigators at the university and facilitates sharing of these resources within the
Estelle Wall, Jonathan Scoles, Adriane Joo, Ophir Klein, Carlo Quinonez, Jeffrey O. Bush, Gail R. Martin, Diana J. Laird   +7 more
doaj   +1 more source