Results 21 to 30 of about 279,987 (320)

Dissecting the Roles of Gonadotropin-Inhibitory Hormone in Mammals: Studies Using Pharmacological Tools and Genetically Modified Mouse Models. [PDF]

Front Endocrinol (Lausanne), 2015
Leon S, Tena-Sempere M.
europepmc   +2 more sources

Inhibition of spontaneous and experimental lung metastasis of soft-tissue sarcoma by tumor-targeting Salmonella typhimurium A1-R. [PDF]

, 2014
Prognosis of patients with lung metastases of soft-tissue sarcoma is still poor. Therefore, novel systemic therapy is needed to improve the survival of soft-tissue sarcoma.
Baek, Kyung-Eun, Bouvet, Michael, Hayashi, Katsuhiro, Hiroshima, Yukihiko, Hoffman, Robert M, Kimura, Hiroaki, Matsumoto, Yasunori, Miwa, Shinji, Tsuchiya, Hiroyuki, Uehara, Fuminari, Yamamoto, Mako, Yamamoto, Norio, Yano, Shuya, Zhang, Yong, Zhao, Ming   +14 more
core   +21 more sources

Genetically Modified <i>Lactococcus lactis</i> Hypersecreting IL-1Ra Improves Glucose Metabolism and Modulates the Gut Microbiota in an Obese Mouse Model. [PDF]

J Diabetes Res
Yoda M, Nomura N, Yoda S, Kagotani M, Murakami A, Namai F, Fujii T, Tochio T, Sato T, Shimosato T.   +9 more
europepmc   +2 more sources

Genetically Modified Mouse Mesenchymal Stem Cells Expressing Non-Structural Proteins of Hepatitis C Virus Induce Effective Immune Response. [PDF]

Vaccines (Basel), 2020
Masalova OV, Lesnova EI, Klimova RR, Momotyuk ED, Kozlov VV, Ivanova AM, Payushina OV, Butorina NN, Zakirova NF, Narovlyansky AN, Pronin AV, Ivanov AV, Kushch AA.   +12 more
europepmc   +3 more sources

Ocular surface mucins and local inflammation--studies in genetically modified mouse lines. [PDF]

BMC Ophthalmol, 2015
Shirai K, Saika S.
europepmc   +3 more sources

miR-23a/b clusters are not essential for the pathogenesis of osteoarthritis in mouse aging and post-traumatic models

Frontiers in Cell and Developmental Biology, 2023
Osteoarthritis (OA), the most prevalent aging-related joint disease, is characterized by insufficient extracellular matrix synthesis and articular cartilage degradation and is caused by various risk factors including aging and traumatic injury.
Yusuke Fujiwara, Chenyang Ding, Yohei Sanada, Yohei Sanada, Dilimulati Yimiti, Masakazu Ishikawa, Masakazu Ishikawa, Tomoyuki Nakasa, Tomoyuki Nakasa, Naosuke Kamei, Kazunori Imaizumi, Martin K. Lotz, Takayuki Akimoto, Shigeru Miyaki, Shigeru Miyaki, Nobuo Adachi   +15 more
doaj   +1 more source

Post-genomic era in agriculture and veterinary science: successful and proposed application of genetic targeting technologies

Frontiers in Veterinary Science, 2023
Gene editing tools have become an indispensable part of research into the fundamental aspects of cell biology. With a vast body of literature having been generated based on next generation sequencing technologies, keeping track of this ever-growing body ...
Ali Mazloum, Maxim Karagyaur, Roman Chernyshev, Antoinette van Schalkwyk, Antoinette van Schalkwyk, Ma Jun, Fu Qiang, Alexander Sprygin   +7 more
doaj   +1 more source

Genetically modified mouse models addressing gonadotropin function

Reproductive Biology, 2014
The development of genetically modified animals has been useful to understand the mechanisms involved in the regulation of the gonadotropin function. It is well known that alterations in the secretion of a single hormone is capable of producing profound reproductive abnormalities.
Laura D. Ratner, Susana B. Rulli, Ilpo T. Huhtaniemi   +2 more
  +7 more sources

Generation of an immortalized mouse embryonic palatal mesenchyme cell line. [PDF]

PLoS ONE, 2017
Palatogenesis is a complex morphogenetic process, disruptions in which result in highly prevalent birth defects in humans. In recent decades, the use of model systems such as genetically-modified mice, mouse palatal organ cultures and primary mouse ...
Katherine A Fantauzzo, Philippe Soriano
doaj   +1 more source

Animal models for COVID-19: advances, gaps and perspectives

Signal Transduction and Targeted Therapy, 2022
COVID-19, caused by SARS-CoV-2, is the most consequential pandemic of this century. Since the outbreak in late 2019, animal models have been playing crucial roles in aiding the rapid development of vaccines/drugs for prevention and therapy, as well as ...
Changfa Fan, Yong Wu, Xiong Rui, Yuansong Yang, Chen Ling, Susu Liu, Shunan Liu, Youchun Wang   +7 more
doaj   +1 more source