Results 11 to 20 of about 279,987 (320)

Two new genetically modified mouse alleles labeling distinct phases of retinal ganglion cell development by fluorescent proteins. [PDF]

Dev Dyn, 2020
Ge Y, Wu F, Cheng M, Bard J, Mu X.
europepmc   +5 more sources

Eradication of Aspiculuris tetraptera in various immunodeficient mouse models using ivermectin: a case report [PDF]

Laboratory Animal Research
Background Despite advancements in laboratory animal facility management, pinworm infections remain a persistent issue in immunodeficient mouse colonies.
Ji-Hun Lee, Eun-Seon Yoo, Na-Won Kim, Han-Bi Jeong, Ah-Reum Kang, Sun-Min Seo, Young-Jun Park, Byeong-Cheol Kang, Yang-Kyu Choi   +8 more
doaj   +2 more sources

Proposed criteria for the evaluation of the scientific quality of mandatory rat and mouse feeding trials with whole food/feed derived from genetically modified plants [PDF]

, 2016
In recent years, animal feeding trials conducted with whole food/feed have been a focal issue in the controversy on the safety assessment of genetically modified (GM) plants and derived food/feed.
Custers, René, Döhring, Janine, Einspanier, Ralf, Glandorf, Debora C. M., Kohl, Christian, Kok, Esther J., Pla, Maria, Schmidt, Kerstin, Sharbati, Jutta, Voet, Hilko van der [u.v.m.]   +9 more
core   +3 more sources

Testing genetically modified food in mouse models

, 2013
Mit Hilfe der Gentechnik ist es möglich gezielte Erbinformationen in Nutzpflanzen zu ändern. In der australischen CSIRO Plant Industrie wurde die genetisch veränderte Nutzpflanze (Pisum sativum) entwickelt. Wissenschaftliche Ergebnisse zeigten, dass das Protein α-Amylase-Inhibitor (AAI) vorkommend in Bohnen, Pflanzen vor schädlichen Käfern beschützt ...
Hui-Yi Lee
openalex   +2 more sources

Altered balance of excitatory and inhibitory learning in a genetically modified mouse model of glutamatergic dysfunction relevant to schizophrenia. [PDF]

Sci Rep, 2017
Sanderson DJ, Lee A, Sprengel R, Seeburg PH, Harrison PJ, Bannerman DM.   +5 more
europepmc   +3 more sources

Novel Genetically Modified Mouse Model to Assess Soman-Induced Toxicity and Medical Countermeasure Efficacy: Human Acetylcholinesterase Knock-in Serum Carboxylesterase Knockout Mice. [PDF]

Int J Mol Sci, 2021
Marrero-Rosado BM, Stone MF, de Araujo Furtado M, Schultz CR, Cadieux CL, Lumley LA.   +5 more
europepmc   +3 more sources

Drug-metabolizing enzyme, transporter, and nuclear receptor genetically modified mouse models. [PDF]

Drug Metab Rev, 2011
Determining the in vivo significance of a specific enzyme, transporter, or xenobiotic receptor in drug metabolism and pharmacokinetics may be hampered by gene multiplicity and complexity, levels of expression, and interaction between various components involved.
Jiang XL, Gonzalez FJ, Yu AM.
europepmc   +4 more sources

Genetically modified mouse models of cancer invasion and metastasis.

Drug Discov Today Dis Models, 2011
Tumor invasion and metastasis is a multi-step process that requires adaptation of cancer cells to conditions that they encounter during their journey to distant body sites. Understanding the molecular processes that underlie this adaptation is of exceeding importance because most cancer patients die because of metastases rather than primary tumors.
Rampetsreiter P, Casanova E, Eferl R.
europepmc   +2 more sources

A novel genetically modified mouse seizure model for evaluating anticonvulsive and neuroprotective efficacy of an A₁ adenosine receptor agonist following soman intoxication. [PDF]

Toxicol Appl Pharmacol, 2023
Shih TM.
europepmc   +3 more sources

Lipidomic and metabolomic characterization of a genetically modified mouse model of the early stages of human type 1 diabetes pathogenesis. [PDF]

Metabolomics, 2016
Overgaard AJ, Weir JM, De Souza DP, Tull D, Haase C, Meikle PJ, Pociot F.   +6 more
europepmc   +3 more sources