Results 41 to 50 of about 7,798,465 (289)
Supervised Machine Learning for Population Genetics: A New Paradigm
Trends in Genetics, 2018 As population genomic datasets grow in size, researchers are faced with the daunting task of making sense of a flood of information. To keep pace with this explosion of data, computational methodologies for population genetic inference are rapidly being ...
Daniel R. Schrider, A. Kern
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm +11 more
wiley +1 more source
The Etruscans: A Population-Genetic Study [PDF]
The American Journal of Human Genetics, 2004 The origins of the Etruscans, a non-Indo-European population of preclassical Italy, are unclear. There is broad agreement that their culture developed locally, but the Etruscans' evolutionary and migrational relationships are largely unknown. In this study, we determined mitochondrial DNA sequences in multiple clones derived from bone samples of 80 ...
C. Vernesi +12 more
openaire +6 more sources
Definitions, 2020 There are thousands of ebooks available to download legally – either because their copyright has expired, or because their authors have chosen to release them without charge.
H. R. Johnston +2 more
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook +6 more
wiley +1 more source
THE POPULATION GENETICS OF SPERM DISPLACEMENT [PDF]
Genetics, 1977 ABSTRACT This article reports the results of some sperm displacement experiments, as well as the results of a theoretical study of selection arising from genetic differences in displacing ability. The experimental work involved the use of three genetic marker stocks in double and triple matings.
Prout, Timothy, Bundgaard, Jørgen
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Population Genetics of Translational Robustness [PDF]
Genetics, 2006 Abstract Recent work has shown that expression level is the main predictor of a gene's evolutionary rate and that more highly expressed genes evolve slower. A possible explanation for this observation is selection for proteins that fold properly despite mistranslation, in short selection for translational robustness.
Wilke, Claus O., Drummond, D. Allan
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A POPULATION GENETIC THEORY OF CANALIZATION [PDF]
Evolution, 1997 Canalization is the suppression of phenotypic variation. Depending on the causes of phenotypic variation, one speaks either of genetic or environmental canalization. Genetic canalization describes insensitivity of a character to mutations, and the insensitivity to environmental factors is called environmental canalization.
Günter P, Wagner +2 more
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The theoretical approach to population genetics
, 2018 Population genetics is the study of gene variation within or between populations. It deals with the allele frequencies in a given population and the forces, which might change this.
Al Ghafri, Mataab K.
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The structure of idealization in biological theories: the case of the Wright-Fisher model. [PDF]
, 2012 In this paper we present a new framework of idealization in biology. We characterize idealizations as a network of counterfactual and hypothetical conditionals that can exhibit different “degrees of contingency”.
Xavier, Donato Rodriguez +5 more
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