Results 251 to 260 of about 50,453 (282)
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The Genetics and Epigenetics of Fatigue
PM&R, 2010AbstractFatigue is a common symptom and includes both physical and mental components. It can be associated with a variety of different syndromes and diseases, but in many cases is not associated with other comorbid conditions. Most humans have experienced acute fatigue in relation to different stressors.
Landmark-Høyvik H +7 more
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New Insights into the Genetics and Epigenetics of Aging Plasticity [PDF]
Genes, 2023 Liu B
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Genetics and epigenetics of osteoarthritis
Maturitas, 2012Osteoarthritis (OA) is a common age-related disease that affects the tissues of the synovial joint, leading to loss of function and pain. It impacts on both patient morbidity and mortality. It is a complex, polygenic disease that lacks any large-effect susceptibility loci.
Reynard LN, Loughlin J
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Genetics and epigenetics of hepatoblastoma
Pediatric Blood & Cancer, 2012AbstractA number of unique genetic features are observed in hepatoblastoma that have provided insights into the origins of hepatoblastoma. Hallmark cytogenetic changes in hepatoblastoma include the acquisition of additional copies of whole chromosomes and a recurring unbalanced translocation involving 1q.
Gail E, Tomlinson, Roland, Kappler
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The genetics of cognitive epigenetics
Neuropharmacology, 2014Cognitive disorders (CDs) are a heterogeneous group of disorders for which the genetic foundations are rapidly being uncovered. The large number of CD-associated gene mutations presents an opportunity to identify common mechanisms of disease as well as molecular processes that are of key importance to human cognition.
Kleefstra, T. +7 more
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Genetics, epigenetics, and causation
American Journal of Orthodontics, 1981Abstract Much of the continuing controversy concerning the roles of genomic and nongenomic (epigenetic) processes in the regulation (causation) of growth is resolved by an analysis of the several types of causation. It can be shown that the combination of genomic and epigenetic factors is a necessary cause of craniofacial growth.
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Nutrition and Health, 2006
In the post human-genome area, the challenge is to derive details of heritable variation in relation to how human variation reflects adaptation to the different environments. Heterozygote advantage represents a superior genetic adaptation presumably explaining the presence of the allele at frequencies above those to be expected from a simple ...
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In the post human-genome area, the challenge is to derive details of heritable variation in relation to how human variation reflects adaptation to the different environments. Heterozygote advantage represents a superior genetic adaptation presumably explaining the presence of the allele at frequencies above those to be expected from a simple ...
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[Genetics and epigenetics of schizophrenia].
La Clinica terapeutica, 2013Schizophrenia is a severe psychiatric disorder with an estimate prevalence of 0.3-0.7%. Studies on family aggregation showed a higher incidence of disease among family members of affected people. This observation lead to formulate the hypothesis that schizophrenia could be inheritable, but twin studies have shown a concordance of disease between ...
Fabi, E, Fusco, A, Valiante, M, Celli, R
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Genetics and epigenetics in vitiligo
Journal of Dermatological ScienceVitiligo, a complex autoimmune disorder characterized by melanocyte destruction, arises from an intricate interplay of genetic, epigenetic, immune, and environmental factors. Genome-wide association studies (GWAS) have identified over 50 susceptibility loci, including key genes within the MHC region and those involved in immunity, oxidative stress, and
Ken, Okamura, Tamio, Suzuki
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The genetic and epigenetic basis of ependymoma
Child's Nervous System, 2009Although ependymoma is the third most common pediatric brain tumor, we know little about the genetic/epigenetic basis of its initiation, maintenance, or progression. This is due in part to the heterogeneity of the disease, as well as the small sample size of the cohorts analyzed in most studies.Many of the genetic aberrations identified to date are ...
Stephen C, Mack, Michael D, Taylor
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