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Bridging the Diagnostic Gap: Enhancing Orthopedic Infection Management through Laboratory Diagnostics in Nepal. [PDF]
JNMA J Nepal Med AssocKhadka RB, Parajuli S, Pahari N.
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GeneXpert for Diagnosis of Tubercular Meningitis
The Indian Journal of Pediatrics, 2016Diagnosis of tubercular meningitis (TBM) is difficult in children. The GeneXpert MTB/RIF assay has been recommended by WHO in 2013 to be used in children and in extra pulmonary clinical specimens. The present study was designed to assess the diagnostic utility of GeneXpert in detecting Mycobacterium tuberculosis in cerebrospinal fluid (CSF) in TBM ...
Rakesh, Bhatia +4 more
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Diagnosis of extrapulmonary tuberculosis by GeneXpert MTB/RIF Ultra assay
Expert Review of Molecular Diagnostics, 2023Diagnosis of extrapulmonary tuberculosis (EPTB) is an arduous task owing to different anatomical locations, unusual clinical presentations, and sparse bacillary load in clinical specimens. Although GeneXpert® MTB/RIF is a windfall in TB diagnostics including EPTB, it yields low sensitivities but high specificities in many EPTB specimens.
Promod Mehta, Bhawna Dahiya
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Pediatric Infectious Disease Society of the Philippines Journal, 2021
Background: Pulmonary TB in children remains to be a burden in the Philippines. Diagnosis remains to be a challenge for pediatricians due to its paucibacillary nature, difficulty in obtaining specimens, cost of test as well as the varied sensitivity of the different tests available.
Joy Morcilla +2 more
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Background: Pulmonary TB in children remains to be a burden in the Philippines. Diagnosis remains to be a challenge for pediatricians due to its paucibacillary nature, difficulty in obtaining specimens, cost of test as well as the varied sensitivity of the different tests available.
Joy Morcilla +2 more
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GeneXpert Testing: Applications for Clinical Microbiology, Part II
Clinical Microbiology Newsletter, 2008The impact of rapid polymerase chain reaction (PCR) technology on infectious disease testing is continuing to evolve outside the realm of a centralized laboratory. The GeneXpert Dx system is the first unit dose, near-point-of-care molecular device commercially available.
Elizabeth M. Marlowe, Donna M. Wolk
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Democratizing molecular diagnostics: the GeneXpert®enterovirus assay
Expert Opinion on Medical Diagnostics, 2008Few clinical scenarios are as diagnostically demanding as the workup of acute meningitis in the emergency room setting. In humans, most cases of meningitis are due to enteroviral infection, which usually resolves with supportive care and does not generally require hospitalization.
Seema R, Patel +3 more
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Comparative Analysis of Genexpert MTB/Rif version 4 and Genexpert MTB/Rif Ultra on Frozen Sputum
2021Objectives: The aim of this study was to carry out a comparative analysis using Genexpert MTB/Rif Ultra (Ultra) on clinical samples of frozen sputum previously analyzed on Genexpert MTB/Rif version 4 (Xpert)and Mycobacterium Growth Indicator Tube (MGIT) culture.Design: The study employed both retrospective and prospective cross sectional design.Setting:
Zvinoera, K. +5 more
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LPA or GeneXpert in the diagnosis of multidrug-resistant tuberculosis.
Pneumologia (Bucharest, Romania), 2018Facing a constant increase of multidrug-resistant tuberculosis (MDR-TB), there is large need for routine use of new diagnostic tests, based on molecular techniques that allow both a rapid diagnosis for TB complex and rapid identification of resistance mutations.
Roxana, Mindru +2 more
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