Results 221 to 230 of about 10,751,278 (348)

Glossary of Bioinformatics Terms [PDF]

open access: yes, 2015
National Human Genome Research Institute
core   +1 more source

Genome sequence of the human malaria parasite Plasmodium falciparum

open access: yesNature, 2002
M. Gardner   +44 more
semanticscholar   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

open access: yesFEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy   +14 more
wiley   +1 more source

REPrise: de novo interspersed repeat detection using inexact seeding. [PDF]

open access: yesMob DNA
Takeda A   +4 more
europepmc   +1 more source

Global variation in copy number in the human genome

open access: yesNature, 2006
R. Redon   +49 more
semanticscholar   +1 more source

Tryptophan‐sensing receptor GPR142 expression levels are directly regulated by proinflammatory cytokines in ghrelin‐producing cells

open access: yesFEBS Open Bio, EarlyView.
GPR142, a tryptophan‐sensing receptor, stimulates gastrointestinal hormones like ghrelin and is linked to inflammation regulation. Proinflammatory cytokines suppress ghrelin production, while tryptophan levels decrease via IDO1 activation. Our findings reveal that proinflammatory cytokines directly regulate GPR142 expression in ghrelin‐producing cells,
Yoko Ueda   +15 more
wiley   +1 more source

Fully resolved genome assembly of a <i>Macrococcus bovicus</i> isolated from a human skin infection. [PDF]

open access: yesMicrobiol Resour Announc
Fernandez JE   +4 more
europepmc   +1 more source

A potential tumor suppressor role of PLK2 in glioblastoma

open access: yesFEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia   +5 more
wiley   +1 more source

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