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Adaptation of Marine Heterotrophic Protists to Long‐Term Warming Selection
Our study unraveled profitable adaptations of marine protozoa to long‐term warming. The optimal temperature, maximum growth rates, cell homeostasis, and cell size significantly increased after warming adaptation, suggesting a resilient future for this functional group.
Mengwen Pang+7 more
wiley +1 more source
ABSTRACT Introduction Nonhuman primates (NHPs) can transmit zoonotic diseases to humans because of their close genetic relationship, facilitating the cross‐species transmission of certain pathogens. In Thailand, Macaca is the most common NHP genus and their inhabits area are in close proximity of human, particularly in urban and suburban areas, where ...
Sarin Suwanpakdee+9 more
wiley +1 more source
DNA Repair in Pathogenic Eukaryotic Cells: Insights from Comparative Genomics of Parasitic Protozoan
Numerous external and internal DNA damaging agents can affect genetic material to produce single-strand breaks (SSB), double strand breaks (DSB), interand intra-strand cross-links in the form of cyclobutane pyrimidine dimers and (6-4)-photoproducts, oxidation and alkylation of bases, or formation of bulky chemical adducts.
Mavil López-Casamichana+3 more
openaire +4 more sources
Martin T. Swain+4 more
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A population genomics approach to host defense in a bumblebee-protozoan model system
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Single-cell genome sequencing of protozoan parasites
Trends in Parasitology, 2021Despite considerable genetic variation within hosts, most parasite genome sequencing studies focus on bulk samples composed of millions of cells. Analysis of bulk samples is biased toward the dominant genotype, concealing cell-to-cell variation and rare variants.
Aliou Dia, Ian H. Cheeseman
openaire +2 more sources
Telomerase ribonucleoprotein and genome integrity—An emerging connection in protozoan parasites
WIREs RNA, 2021AbstractTelomerase has an established role in telomere maintenance in eukaryotes. However, recent studies have begun to implicate telomerase in cellular roles beyond telomere maintenance. Specifically, evidence is emerging of cross‐talks between telomerase mediated telomere homeostasis and DNA repair pathways.
Justin Alexander Davis+1 more
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Nature Reviews Microbiology, 2005
The recent completion of five new protozoan parasite genomes should lead to an improved understanding of their biology and, through comparative genomics, shed light on protozoan genome diversity and evolution.
Matthew Berriman+2 more
openaire +2 more sources
The recent completion of five new protozoan parasite genomes should lead to an improved understanding of their biology and, through comparative genomics, shed light on protozoan genome diversity and evolution.
Matthew Berriman+2 more
openaire +2 more sources