Results 41 to 50 of about 1,052,313 (231)

Highly syntenic and yet divergent: a tale of two Theilerias [PDF]

, 2009
The published genomic sequences of the two major host-transforming Theileria species of cattle represent a rich resource of information that has allowed novel bioinformatic and experimental studies into these important apicomplexan parasites. Since their
Bishop, R., Chaussepied, M., de Villiers, E.P., Langsley, G., Shiels, B., Skilton, R., Sunter, J., Tait, A., Weir, W.   +8 more
core   +1 more source

Pseudocohnilembus persalinus genome database - the first genome database of facultative scuticociliatosis pathogens

BMC Genomics, 2018
Background Pseudocohnilembus persalinus, a unicellular ciliated protozoan, is one of commonest facultative pathogens. We sequenced the macronuclear genome of P. persalinus in 2015, which provided new insights into its pathogenicity.
Wei Wei, Kai Chen, Wei Miao, Wentao Yang, Jie Xiong   +4 more
doaj   +1 more source

The compact genome of Giardia muris reveals important steps in the evolution of intestinal protozoan parasites

bioRxiv, 2019
Diplomonad parasites of the genus Giardia have adapted to colonizing different hosts, most notably the intestinal tract of mammals. The human-pathogenic Giardia species, Giardia intestinalis, has been extensively studied at the genome and gene expression
Feifei Xu, A. Jiménez-González, Elin Einarsson, Ásgeir Ástvaldsson, D. Peirasmaki, L. Eckmann, J. Andersson, S. Svärd, J. Jerlström-Hultqvist   +8 more
semanticscholar   +1 more source

Discovery of mating in the major African livestock pathogen Trypanosoma congolense [PDF]

, 2009
The protozoan parasite, Trypanosoma congolense, is one of the most economically important pathogens of livestock in Africa and, through its impact on cattle health and productivity, has a significant effect on human health and well being.
A MacLeod, A MacLeod, A Tait, A Tait, A Tait, AC Hoare, AL Hughes, Alana Black, Alison Tweedie, AM Schurko, Andreas Schoenefeld, Andy Tait, Annette MacLeod, B Haubold, C. Michael R. Turner, Christiane Hertz-Fowler, CJ Young, D Faye, DK Masiga, DL Hartl, DR Page, F Balloux, FG Razakandrainibe, G Benson, G Evanno, Gina L. Pinchbeck, GL Pinchbeck, J Maynard Smith, J Sternberg, JK Gashumba, JK Pritchard, JR Stevens, JR Stevens, K Lewicka, Laurent Rénia, Liam J. Morrison, LJ Morrison, LJ Morrison, LJ Morrison, M Hope, M Koffi, M Raymond, M Tibayrenc, M Tibayrenc, M Tibayrenc, MA Ramesh, MW Gaunt, NM El-Sayed, P Stenberg, PH Holmes, PMA Shaw, R Peakall, Robert M. Christley, S Geerts, T de Meeus, T Mzilahowa, TJ Anderson, V Jamonneau, W Gibson, W Gibson, W Gibson, W Gibson, W Weir, WP Hedrick   +63 more
core   +15 more sources

Genome-wide localization of histone variants in Toxoplasma gondii implicates variant exchange in stage-specific gene expression

BMC Genomics, 2022
Background Toxoplasma gondii is a protozoan parasite that differentiates from acute tachyzoite stages to latent bradyzoite forms in response to environmental cues that modify the epigenome. We studied the distribution of the histone variants CenH3, H3.3,
Sheila Nardelli, Natalie C. Silmon de Monerri, Laura Vanagas, Xiaonan Wang, Zoi Tampaki, W. J. Sullivan, S. Angel, Kami Kim   +7 more
semanticscholar   +1 more source

Identifying and Resolving Genome Misassembly Issues Important for Biomarker Discovery in the Protozoan Parasite, Cryptosporidium

Bioinformatics, 2019
Cryptosporidium is a protozoan parasite that causes a diarrhoeal disease in humans, and which may be spread by swimming pools or infected municipal water supplies. It can be a serious health risk for individuals with weakened immune systems. Genomics has
Arthur Morris, J. Pachebat, G. Robinson, R. Chalmers, M. Swain   +4 more
semanticscholar   +1 more source

Cloning and expression of codon-optimized recombinant darbepoetin alfa in Leishmania tarentolae T7-TR [PDF]

, 2016
Darbepoetin alfa is an engineered and hyperglycosylated analog of recombinant human erythropoietin (EPO) which is used as a drug in treating anemia in patients with chronic kidney failure and cancer.
Fard-Esfahani, P., Golavar, R., Khajeniazi, S., Kianmehr, A., Mahrooz, A., Mostafavi, S.S., Oladnabi, M., Omidinia, E., Rouintan, M.   +8 more
core   +1 more source

Functional annotation and comparative genomics analysis of Balamuthia mandrillaris reveals potential virulence-related genes

Scientific Reports, 2023
Balamuthia mandrillaris is a pathogenic protozoan that causes a rare but almost always fatal infection of the central nervous system and, in some cases, cutaneous lesions. Currently, the genomic data for this free-living amoeba include the description of
Alejandro Otero-Ruiz, Libia Zulema Rodriguez-Anaya, Fernando Lares-Villa, Luis Fernando Lozano Aguirre Beltrán, Luis Fernando Lares-Jiménez, Jose Reyes Gonzalez-Galaviz, Abraham Cruz-Mendívil   +6 more
doaj   +1 more source

A new landscape of host–protozoa interactions involving the extracellular vesicles world [PDF]

, 2018
This version is free to view and download for private research and study only. Not for re-distribution, re-sale or use in derivative works. © Cambridge University Press 2018Extracellular vesicles (EVs) are released by a wide number of cells including ...
Bruno Gavinho, Combes, Dlugonska, Hart, Ingrid Evans-Osses, Izadora Volpato Rossi, Jameel Inal, Kho, Lechartier, Marcel I. Ramirez, Nten, Zingales   +11 more
core   +2 more sources

G-Quadruplex Identification in the Genome of Protozoan Parasites Points to Naphthalene Diimide Ligands as New Antiparasitic Agents

Journal of Medicinal Chemistry, 2018
G-quadruplexes (G4) are DNA secondary structures that take part in the regulation of gene expression. Putative G4 forming sequences (PQS) have been reported in mammals, yeast, bacteria, and viruses.
E. Belmonte-Reche, M. Martínez-García, A. Guédin, M. Zuffo, M. Arévalo-Ruiz, F. Doria, J. Campos-Salinas, M. Maynadier, Jose-Juan Lopez-Rubio, M. Freccero, J. Mergny, J. M. Pérez-Victoria, J. C. Morales   +12 more
semanticscholar   +1 more source