Results 31 to 40 of about 3,155,630 (345)

Developing Novel Therapeutic Strategies Against Ring Finger Protein 213 Vasculopathy: Is It an Achievable Goal?

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
See Article Choi et ...
Minghua Liu, Jose Gutierrez
doaj   +1 more source

A genome-wide association study of anorexia nervosa. [PDF]

, 2014
Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by dangerously low body weight. Neither candidate gene studies nor an initial genome-wide association study (GWAS) have yielded significant and replicated results.
A A van Elburg, A Bruson, A Farmer, A Favaro, A Hinney, A Julia, A Karwautz, A Keski-Rahkonen, A Lundervold, A Metspalu, A Palotie, A Raevuori, A Rajewski, A S Kaplan, A Scherag, A Schosser, A Slopien, A Tortorella, A Tsitsika, A Versini, Adrian Hill, Alexander P Maxwell, Anna Dominiczak, Audrey Duncanson, B Ding, B Herpertz-Dahlmann, B P C Koeleman, C Boni, C de Kovel, C Dina, C E Hilliard, C Finan, C M Bulik, C M Lewis, C S Franklin, C Taico, Carl A Anderson, Christopher S Franklin, Cordelia Langford, Cordelia Langford, Cynthia M Bulik, D A Collier, D Degortes, D Dikeos, D Koubek, D Li, D M Dick, D Martaskova, D Pinto, D Rujescu, D W Logan, David A Collier, David P Strachan, Douglas Simpkin, E Docampo, E F Van Furth, E Merl, E Strengman, E Tenconi, E Widén, E Zeggini, Eleftheria Zeggini, Emma Gray, F Fernández-Aranda, F Gonidakis, F Rybakowski, F Tozzi, Fredrik O Vannberg, G Breen, G Dedoussis, G Escaramís, G Gambaro, G Kalsi, G Komaki, G P S Knudsen, G R S Ritchie, G Wagner, Graeme Alexander, Graham Lord, H Aschauer, H Hakonarson, H Imgart, H Inoko, H Papezova, H-E Wichmann, Hannah Blackburn, I Giegling, I Jaussent, I Meulenbelt, I Ntalla, I Reinvang, I Tachmazidou, J A B Floyd, J C Barrett, J Dackor, J E DeSocio, J H Baker, J Hauser, J Hebebrand, J Hendriks, J Huemer, J I Hudson, J K O'Toole, J Kaprio, J L Kennedy, J Lissowska, J P Szatkiewicz, J Pantel, J Treasure, James A B Floyd, Jeffrey C Barrett, Jeffrey C Barrett, Jennifer Sambrook, Jonathan Stephens, K Bühren, K Egberts, K Fischer, K Kiezebrink, K L Klump, K Männik, K Tziouvas, L Alfredsson, L Carlberg, L Foretova, L Karhunen, L Klareskog, L M Huckins, L M Thornton, L Padyukov, L Peltonen, L Slachtova, L Southam, Leena Peltonen, Linda Morgan, M C T Slof-Op 't Landt, M Clementi, M de Zwaan, M Dmitrzak-Weglarz, M Forzan, M Gratacos, M J H Kas, M K Brandys, M Maj, M Mattingsdal, M Navratilova, M Roberts, Mathew Gillman, N J Schork, N Ramoz, N Soranzo, N Szeszenia-Dabrowska, N W Rayner, Neil Sheerin, Nicole Soranzo, Nicole Soranzo, null null, O A Andreassen, O S P Davis, P Courtet, P E Slagboom, P F Sullivan, P Gorwood, P Lichtenstein, P McGuffin, P Monteleone, P Santonastaso, Pamela Whittaker, Peter J Conlon, R A H Adan, R A Ophoff, R Burghardt, R D Cone, R D Levitan, R Rabionet, R Sladek, Ralph McGinnis, Richard N Sandford, S Cichon, S Cohen-Woods, S E Trace, S Ehrlich, S Gallinger, S Guillaume, S Helder, S Herms, S Jiménez-Murcia, S Le Hellard, S Marsal, S Ripatti, S Scherag, S Schreiber, S W Scherer, S Zerwas, S Zipfel, Sarah E Hunt, Sarah Edkins, Simon Potter, Stephen S Rich, Suna Onengut-Gumuscu, Susan M Ring, T Ando, T Esko, T Espeseth, T Reichborn-Kjennerud, U N Danner, U Schmidt, V Bencko, V Boraska, V Gaborieau, V Janout, V M Steen, W H Berrettini, W Herzog, Wei-Min Chen, Wendy L McArdle, Willem H Ouwehand, X Estivill, Y Guo, Z Yilmaz   +218 more
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Genetic Pathways to Insomnia

Brain Sciences, 2016
This review summarizes current research on the genetics of insomnia, as genetic contributions are thought to be important for insomnia etiology. We begin by providing an overview of genetic methods (both quantitative and measured gene), followed by a ...
Mackenzie J. Lind, Philip R. Gehrman
doaj   +1 more source

Genome-wide association study of behavioural and psychiatric features in human prion disease. [PDF]

, 2015
Prion diseases are rare neurodegenerative conditions causing highly variable clinical syndromes, which often include prominent neuropsychiatric symptoms.
Carswell, C, Collinge, J, Lowe, J, Lukic, A, MacKay, A, Mead, S, Porter, MC, Rudge, P, Thompson, AG, Uphill, J   +9 more
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ICAM-1 molecular mechanism and genome wide SNP's association studies

Indian Heart Journal, 2015
Macrophages transformed foam cell formation occurs as a result of leukocyte accumulation mediated through intercellular adhesion molecule 1 (ICAM1), vascular cell adhesion molecule 1 (VCAM1), and E-selectin, secreted by inflamed or damaged endothelium ...
C. Anbarasan, M. Bavanilatha, K. Latchumanadhas, S. Ajit Mullasari   +3 more
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Genome-wide Association Study of Chicken Plumage Pigmentation [PDF]

Asian-Australasian Journal of Animal Sciences, 2013
To increase plumage color uniformity and understand the genetic background of Korean chickens, we performed a genome-wide association study of different plumage color in Korean native chickens. We analyzed 60K SNP chips on 279 chickens with GEMMA methods
Mi Na Park, Jin Ae Choi, Kyung-Tai Lee, Hyun-Jeong Lee, Bong-Hwan Choi, Heebal Kim, Tae-Hun Kim, Seoae Cho, Taeheon Lee   +8 more
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Exploring quantitative traits-associated copy number deletions through reanalysis of UK10K consortium whole genome sequencing cohorts

BMC Genomics, 2023
Objectives We performed comprehensive association analyses of common high-confidence gnomAD-reported copy number deletions (CNDs) with 60 quantitative traits from UK10K consortium WGS data.
Sejoon Lee, Jinho Kim, Jung Hun Ohn
doaj   +1 more source

Psoriasis: An Immunogenetic Perspective

Global Medical Genetics, 2022
Psoriasis is an erythematous-squamous dermatosis with a polygenic inheritance history. Both environmental and genetic factors play a role in the etiology of the disease.
Ayca Kocaaga, Mustafa Kocaaga
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Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration [PDF]

, 2011
AIMS: To evaluate the associations of emergent genome-wide-association study-derived coronary heart disease (CHD)-associated single nucleotide polymorphisms (SNPs) with established and emerging risk factors, and the association of genome-wide-association
Angelakopoulou, A, Berry, DJ, Casas, JP, Caulfield, M, Cooper, J, de Faire, U, Deanfield, J, Drenos, F, Fowkes, FG, Gigante, B, Hardy, R, Hingorani, AD, Humphries, SE, Hypponen, E, Ireland, H, Jefferis, BJ, Kivimaki, M, Kuh, D, Kumari, M, Lathrop, M, Laxton, RC, Leander, K, Maniatis, N, Marmot, M, Morris, RW, Motterle, A, Munroe, PB, Palmen, J, Power, C, Price, J, Samani, N, Shah, S, Shah, T, Simpson, IA, Smeeth, L, Sofat, R, Talmud, PJ, Thomson, A, Tzoulaki, I, Verzilli, C, Wallace, C, Whincup, PH, Whittaker, JC, Wong, A, Ye, S   +44 more
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Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

Nature Genetics, 2016
Genetic association studies have identified 215 risk loci for inflammatory bowel disease, thereby uncovering fundamental aspects of its molecular biology.
K. D. de Lange, L. Moutsianas, James C. Lee, C. Lamb, Yang Luo, N. Kennedy, L. Jostins, D. Rice, Javier Gutiérrez-Achury, S. Ji, G. Heap, E. Nimmo, C. Edwards, P. Henderson, C. Mowat, J. Sanderson, J. Satsangi, A. Simmons, D. Wilson, M. Tremelling, A. Hart, C. Mathew, W. Newman, M. Parkes, C. Lees, H. Uhlig, C. Hawkey, N. Prescott, T. Ahmad, J. Mansfield, C. Anderson, J. Barrett   +31 more
semanticscholar   +1 more source