Results 11 to 20 of about 732,792 (264)

Genome wide analysis reveals genetic divergence between Goldsinny wrasse populations

BMC Genetics, 2020
Background Marine fish populations are often characterized by high levels of gene flow and correspondingly low genetic divergence. This presents a challenge to define management units.
Eeva Jansson, Francois Besnier, Ketil Malde, Carl André, Geir Dahle, Kevin A. Glover   +5 more
doaj   +1 more source

Genome wide association analysis for yield related traits in maize

BMC Plant Biology, 2022
Background Understanding the genetic basis of yield related traits contributes to the improvement of grain yield in maize. Results Using 291 excellent maize inbred lines as materials, six yield related traits of maize, including grain yield per plant ...
Tingru Zeng, Zhaodong Meng, Runqing Yue, Shouping Lu, Wenlan Li, Wencai Li, Hong Meng, Qi Sun   +7 more
doaj   +1 more source

FGWAS: Functional genome wide association analysis [PDF]

NeuroImage, 2017
Functional phenotypes (e.g., subcortical surface representation), which commonly arise in imaging genetic studies, have been used to detect putative genes for complexly inherited neuropsychiatric and neurodegenerative disorders. However, existing statistical methods largely ignore the functional features (e.g., functional smoothness and correlation ...
Chao, Huang, Paul, Thompson, Yalin, Wang, Yang, Yu, Jingwen, Zhang, Dehan, Kong, Rivka R, Colen, Rebecca C, Knickmeyer, Hongtu, Zhu   +8 more
openaire   +2 more sources

Genome-wide analysis correlates Ayurveda Prakriti [PDF]

Scientific Reports, 2015
AbstractThe practice ofAyurveda, the traditional medicine of India, is based on the concept of three major constitutional types (Vata, Pitta and Kapha) defined as “Prakriti”. To the best of our knowledge, no study has convincingly correlated genomic variations with the classification ofPrakriti.In the present study, we performed genome-wide SNP (single
Periyasamy Govindaraj, Sheikh Nizamuddin, Sharath Anugula, Vuskamalla Jyothi, Harish Rotti, Ritu Raval, Jayakrishna Nayak, Balakrishna K Bhat, B V Prasanna, Pooja Shintre, Mayura Sule, Kalpana Joshi, Amrish P Dedge, Ramachandra Bharadwaj, G G Gangadharan, Sreekumaran Nair, P. M. Gopinath, Bhushan Patwardhan, Paturu Kondaiah, Kapaettu Satyamoorthy, Marthanda Varma Sankaran Valiathan, Kumarasamy Thangaraj   +21 more
openaire   +3 more sources

Improved statistics for genome-wide interaction analysis. [PDF]

PLoS Genetics, 2012
Recently, Wu and colleagues [1] proposed two novel statistics for genome-wide interaction analysis using case/control or case-only data. In computer simulations, their proposed case/control statistic outperformed competing approaches, including the fast ...
Masao Ueki, Heather J Cordell
doaj   +1 more source

Genome-wide gene and pathway analysis [PDF]

European Journal of Human Genetics, 2010
Current GWAS have primarily focused on testing association of single SNPs. To only test for association of single SNPs has limited utility and is insufficient to dissect the complex genetic structure of many common diseases. To meet conceptual and technical challenges raised by GWAS, we suggest gene and pathway-based GWAS as complementary to the ...
Li, Luo, Gang, Peng, Yun, Zhu, Hua, Dong, Christopher I, Amos, Momiao, Xiong   +5 more
openaire   +2 more sources

Genome-wide analysis of Alu editability [PDF]

Nucleic Acids Research, 2014
A-to-I RNA editing is apparently the most abundant post-transcriptional modification in primates. Virtually all editing sites reside within the repetitive Alu SINEs. Alu sequences are the dominant repeats in the human genome and thus are likely to pair with neighboring reversely oriented repeats and form double-stranded RNA structures that are bound by
L. Bazak, E. Y. Levanon, E. Eisenberg
openaire   +2 more sources

Genome-wide hierarchical mixed model association analysis [PDF]

Briefings in Bioinformatics, 2021
AbstractIn genome-wide mixed model association analysis, we stratified the genomic mixed model into two hierarchies to estimate genomic breeding values (GBVs) using the genomic best linear unbiased prediction and statistically infer the association of GBVs with each SNP using the generalized least square.
Zhiyu Hao, Jin Gao, Yuxin Song, Runqing Yang, Di Liu   +4 more
openaire   +2 more sources

Genome-Wide Analysis of Human Metapneumovirus Evolution. [PDF]

PLoS ONE, 2016
Human metapneumovirus (HMPV) has been described as an important etiologic agent of upper and lower respiratory tract infections, especially in young children and the elderly.
Jin Il Kim, Sehee Park, Ilseob Lee, Kwang Sook Park, Eun Jung Kwak, Kwang Mee Moon, Chang Kyu Lee, Joon-Yong Bae, Man-Seong Park, Ki-Joon Song   +9 more
doaj   +1 more source

Genome Wide Analysis of Amino Acid Transporter Superfamily in Solanum lycopersicum

Plants, 2021
Amino acid transporters (AATs) are integral membrane proteins and have several functions, including transporting amino acids across cellular membranes. They are critical for plant growth and development. This study comprehensively identified AAT-encoding
Fatima Omari Alzahrani
doaj   +1 more source