Results 211 to 220 of about 754,015 (260)

Genome-wide analysis of tandem repeat variation identifies SLC15A4 as a susceptibility gene for idiopathic pulmonary fibrosis

open access: yes
Oketch JW   +15 more
europepmc   +1 more source

Genome-wide analysis of structural variation

Nature Methods, 2021
Phased genomes from diverse human populations are assembled using multiple sequencing technologies.
openaire   +2 more sources

Genome-Wide Analysis of Planarian piRNAs

2023
In planarian flatworms, the piRNA pathway is operated by three PIWI proteins, termed SMEDWI-1, SMEDWI-2, and SMEDWI-3 (SMEDWI = Schmidtea mediterranea PIWI). The interplay between these three PIWI proteins and their associated small noncoding RNAs, termed piRNAs, fuels the outstanding regenerative abilities of planarians, enables tissue homeostasis ...
Andreas, Pittroff   +3 more
openaire   +2 more sources

Genome-Wide Methylation Analysis

2012
The disruption and alteration of genomic methylation patterns is a hallmark of cancer and other disease states. Understanding and characterizing genome-wide methylation will have a profound effect on our understanding of tumorigenesis and provide novel avenues for therapy.
Alexander, Unterberger   +2 more
openaire   +2 more sources

GENOME-WIDE ANALYSIS OF BACTERIAL PROMOTER REGIONS [PDF]

open access: possibleBiocomputing 2003, 2002
Identifying prokaryotic promoter sequences is notoriously difficult and for most sequenced bacterial genomes the promoter sequences are still unknown. Since experimental analysis trails behind sequencing, genome-wide computational promoter discovery is often the only realistic way to discover these sequences in newly sequenced bacterial genomes ...
Eleazar Eskin   +3 more
openaire   +2 more sources

Genome-wide Analysis of Myelodysplastic Syndromes

Current Pharmaceutical Design, 2012
Myelodysplastic syndromes (MDS) are heterogeneous hematopoietic neoplasms characterized by ineffective hematopoiesis and a risk for progression to acute myeloid leukemia. A number of cytogenetic changes have been described that are characteristic to MDS and of clinical relevance; the specific gene targets of these alterations were largely unknown.
Masashi, Sanada, Seishi, Ogawa
openaire   +2 more sources

Genome-wide pathway analysis of a genome-wide association study on Alzheimer’s disease

Neurological Sciences, 2014
The aims of this study were to identify candidate single nucleotide polymorphisms (SNPs) and mechanisms of Alzheimer's disease (AD) and to generate SNP to gene to pathway hypotheses. An AD genome-wide association study (GWAS) dataset that included 370,542 SNPs in 1,000 cases and 1,000 controls of European descent was used in this study.
Young Ho, Lee, Gwan Gyu, Song
openaire   +2 more sources

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