Results 181 to 190 of about 669,401 (295)

A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci

Nature Genetics, 2017
Diana Chang, M. Nalls, Ingileif B. Hallgrímsdóttir, J. Hunkapiller, Marcel P. van der Brug, Fang Cai, G. Kerchner, Gai Ayalon, Baris Bingol, Morgan Sheng, D. Hinds, T. Behrens, A. Singleton, T. Bhangale, R. Graham   +14 more
semanticscholar   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

PP-GWAS: Privacy Preserving Multi-Site Genome-wide Association Studies. [PDF]

Nat Commun
Swaminathan A, Hannemann A, Ünal AB, Pfeifer N, Akgün M.   +4 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Genome-wide association studies and genomic selection for leaf-related traits in maize. [PDF]

Front Plant Sci
Yang X, Wu P, Cui W, Alimu D, Wang K, Ren J.   +5 more
europepmc   +1 more source

The Influence of Type-2 Diabetes on Cataract and their Shared Genetic Basis Through Relevant Genome-wide Association Studies

Janaki Sneha, Saravanan Yogaprabhu, Ranjit Mohan Anjana, Viswanathan Mohan, Venkatesan Radha   +4 more
openalex   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Editorial: Brief research reports in pharmacogenetics and pharmacogenomics: 2022

Frontiers in Pharmacology, 2023
Francesco Sessa, Tarek Magdy, Tarek Magdy, Chonlaphat Sukasem, Chonlaphat Sukasem, George P. Patrinos, George P. Patrinos, George P. Patrinos   +7 more
doaj   +1 more source

Monitoring diversity in genome-wide association studies requires measuring and reporting on immigration-related factors. [PDF]

Front Genet
Tu Y, Fernandez-Rhodes L.
europepmc   +1 more source

Causal relationship between multiple sclerosis and asthma and chronic obstructive pulmonary disease based on genome-wide association study data

Wenhui Cui, Ting-Ting Wu, Keqing Shi, Xin Wang, Shuyu Chen, Mengjun Cao, Aolong Xu, Yingzhi Chong, Xueli Zhang, Qiang Wang   +9 more
openalex   +1 more source