Results 211 to 220 of about 669,401 (295)

Genome-Wide Association Studies Data and Transcriptomics Data Link Herpes Simplex Virus 1 Infection and Parkinson's Disease. [PDF]

Parkinsons Dis
Lu C, Cai X, Simula E, Ercoli T, Solla P, Sechi LA.   +5 more
europepmc   +1 more source

Genome-Wide Association Study of Body Fat Distribution identifies Novel Adiposity Loci and Sex-Specific Genetic Effects [PDF]

, 2017
Mathias Rask‐Andersen, Torgny Karlsson, Weronica E. Ek, Åsa Johansson   +3 more
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Unveiling key genetic determinants of charcoal rot resistance in soybean via genome-wide association studies. [PDF]

Front Plant Sci
Nataraj V, Amrate PK, Ratnaparkhe MB, Maranna S, Rajput LS, Agrawal N, Raghuvanshi R, Pathak K, Mandloi S, Mohare S, Naik K B, Shrivastava MK, Kumawat G, Rajesh V, Gupta S, Chitikineni A, Varshney RK, Singh KH.   +17 more
europepmc   +1 more source

New approaches to population stratification in genome-wide association studies

Nature reviews genetics, 2010
A. Price, N. Zaitlen, D. Reich, N. Patterson   +3 more
semanticscholar   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A Bayesian Model for Paired Data in Genome-Wide Association Studies with Application to Breast Cancer. [PDF]

Entropy (Basel)
Bu Y, Chen M, Xuan Z, Wang X.
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Multi-Genome-Wide association studies provide new insights into the genetic architecture of Varroa resistance in honeybees. [PDF]

BMC Genomics
Davoodi P, Razmkabir M.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source