Results 21 to 30 of about 22,244,058 (261)

Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function [PDF]

open access: yes, 2014
Background: Genome-wide association studies (GWAS) have identified numerous loci influencing cross-sectional lung function, but less is known about genes influencing longitudinal change in lung function.
Wenbo Tang (110161)   +617 more
core   +2 more sources

Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned [PDF]

open access: yes, 2010
Major depressive disorder (MDD) is a common complex disorder with a partly genetic etiology. We conducted a genome-wide association study of the MDD2000+ sample (2431 cases, 3673 screened controls and >1 M imputed single-nucleotide polymorphisms (SNPs)).
D I Boomsma   +145 more
core   +2 more sources

Deriving GWAS summary estimates for paternal smoking in UK biobank: a GWAS by subtraction

open access: yesBMC Research Notes, 2023
Objective To use genome-wide association study (GWAS) by subtraction, a method for deriving novel GWASs from existing summary statistics, to derive genome-wide summary statistics for paternal smoking.
Benjamin Woolf   +3 more
doaj   +1 more source

Large-scale transcriptome-wide association study identifies new prostate cancer risk regions

open access: yesNature Communications, 2018
Genome-wide association studies (GWAS) have identified hundreds of genomic risk regions for prostate cancer. Here, the authors perform a transcriptome wide association study (TWAS) by incorporating prostate cancer GWAS with gene expression data to ...
Nicholas Mancuso   +10 more
doaj   +1 more source

A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain [PDF]

open access: yes, 2014
Background: Neuropathic pain, caused by a lesion or a disease affecting the somatosensory system, is one of the most common complications in diabetic patients.
Palmer, C. N. A.; id_orcid   +21 more
core   +1 more source

Word-based GWAS harnesses the rich potential of genomic data for E. coli quinolone resistance

open access: yesFrontiers in Microbiology, 2023
Quinolone resistance presents a growing global health threat. We employed word-based GWAS to explore genomic data, aiming to enhance our understanding of this phenomenon.
Negin Malekian   +5 more
doaj   +1 more source

The Human Microbiome and the Missing Heritability Problem

open access: yesFrontiers in Genetics, 2017
The “missing heritability” problem states that genetic variants in Genome-Wide Association Studies (GWAS) cannot completely explain the heritability of complex traits.
Santiago Sandoval-Motta   +6 more
doaj   +1 more source

Multi-locus genome-wide association studies for five yield-related traits in rice

open access: yesBMC Plant Biology, 2021
Background Improving the overall production of rice with high quality is a major target of breeders. Mining potential yield-related loci have been geared towards developing efficient rice breeding strategies.
Hua Zhong   +6 more
doaj   +1 more source

Identification of genetic basis of agronomic traits in alfalfa (Medicago sativa subsp. sativa) using Genome Wide Association Studies

open access: yesJournal of Oasis Agriculture and Sustainable Development, 2023
Alfalfa (Medicago sativa L.) is one of the most widely cultivated forage crops due to its high yield, value of nutrients, and adaptation to diverse environments.
Wiem Mnafgui   +4 more
doaj   +1 more source

A Genome-Wide Association Study Identifies Genomic Regions for Virulence in the Non-Model Organism Heterobasidion annosum ss [PDF]

open access: yes, 2013
The dense single nucleotide polymorphisms (SNP) panels needed for genome wide association (GWA) studies have hitherto been expensive to establish and use on non-model organisms.
Brandström Durling, Mikael   +24 more
core   +3 more sources

Home - About - Disclaimer - Privacy