Results 31 to 40 of about 189,144 (345)
Large-scale transcriptome-wide association study identifies new prostate cancer risk regions
Nature Communications, 2018 Genome-wide association studies (GWAS) have identified hundreds of genomic risk regions for prostate cancer. Here, the authors perform a transcriptome wide association study (TWAS) by incorporating prostate cancer GWAS with gene expression data to ...
Nicholas Mancuso +10 more
doaj +1 more source
The Human Microbiome and the Missing Heritability Problem
Frontiers in Genetics, 2017 The “missing heritability” problem states that genetic variants in Genome-Wide Association Studies (GWAS) cannot completely explain the heritability of complex traits.
Santiago Sandoval-Motta +6 more
doaj +1 more source
HLA Class I or Class II and Disease Association: Catch the Difference if You Can [PDF]
, 2017 The association of autoimmune diseases with HLA has been known for many decades. To date, however, the underlying mechanisms have not been fully understood. The recently introduced genome-wide association studies (GWAS) have suggested that several genes
Fiorillo, Mt +3 more
core +2 more sources
Journal of Oasis Agriculture and Sustainable Development, 2023 Alfalfa (Medicago sativa L.) is one of the most widely cultivated forage crops due to its high yield, value of nutrients, and adaptation to diverse environments.
Wiem Mnafgui +4 more
doaj +1 more source
Tissue-specific network-based genome wide study of amygdala imaging phenotypes to identify functional interaction modules [PDF]
, 2017 Motivation: Network-based genome-wide association studies (GWAS) aim to identify functional modules from biological networks that are enriched by top GWAS findings.
Alzheimer’s Disease Neuroimaging Initiative +10 more
core +1 more source
Robust Reference Powered Association Test of Genome-Wide Association Studies
Frontiers in Genetics, 2019 Genome-wide association studies (GWASs) have identified abundant genetic susceptibility loci, GWAS of small sample size are far less from meeting the previous expectations due to low statistical power and false positive results.
Yi Wang +16 more
doaj +1 more source
Robust Tests in Genome-Wide Scans under Incomplete Linkage Disequilibrium [PDF]
, 2009 Under complete linkage disequilibrium (LD), robust tests often have greater power than Pearson's chi-square test and trend tests for the analysis of case-control genetic association studies.
Geller, Nancy +4 more
core +1 more source
Nature Communications, 2018 Genetic loci linked to susceptibility for the common skin cancer cutaneous squamous cell carcinoma (cSCC) have been identified by genome wide association studies (GWAS).
Nilah M. Ioannidis +8 more
doaj +1 more source
Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative
Microbiome, 2018 Background In recent years, human microbiota, especially gut microbiota, have emerged as an important yet complex trait influencing human metabolism, immunology, and diseases.
Jun Wang +26 more
doaj +1 more source
The role of 39 psoriasis risk variants on age of psoriasis onset. [PDF]
, 2013 Recent genome-wide association studies (GWAS) have identified multiple genetic risk factors for psoriasis, but data on their association with age of onset have been marginally explored.
Butler, Daniel +12 more
core +2 more sources