Results 1 to 10 of about 1,051,148 (367)
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis [PDF]
Nature Genetics, 2007 John D. Rioux, Ramnik J. Xavier, Kent D. Taylor, Mark S. Silverberg, Philippe Goyette, Alan Huett, Todd J. Green, Petric Kuballa, M. Michael Barmada, Lisa W. Datta, Yin Yao Shugart, Anne M. Griffiths, Stephan R. Targan, Andrew Ippoliti, Edmond-Jean Bernard, Ling Mei, Dan L. Nicolae, Miguel Regueiro, L. Philip Schumm, A. Hillary Steinhart, Jerome I. Rotter, Richard H. Duerr, Judy H. Cho, Mark J. Daly, Steven R. Brant +24 moreopenalex +2 more sourcesA Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene
Science, 2006 Richard H. Duerr, Kent D. Taylor, Steven R. Brant, John D. Rioux, Mark S. Silverberg, Mark J. Daly, A. Hillary Steinhart, Clara Abraham, Miguel Regueiro, Anne M. Griffiths, Themistocles Dassopoulos, Alain Bitton, Huiying Yang, Stephan R. Targan, Lisa W. Datta, Emily O. Kistner, L. Philip Schumm, Annette T. Lee, Peter K. Gregersen, M. Michael Barmada, Jerome I. Rotter, Dan L. Nicolae, Judy H. Cho +22 moreopenalex +2 more sourcesGenome-wide association study identifies novel breast cancer susceptibility loci
Nature, 2007 Douglas F. Easton, Karen A. Pooley, Alison M. Dunning, Paul D.P. Pharoah, Deborah J. Thompson, Dennis G. Ballinger, Jeffery P. Struewing, Jonathan J. Morrison, Helen I. Field, Robert Luben, Nicholas J. Wareham, Shahana Ahmed, Catherine S. Healey, Richard Bowman, Craig Luccarini, Don Conroy, Mitul Shah, Hannah Munday, Clare Jordan, Barbara Perkins, Judy West, Karen Redman, Kristy Driver, Kerstin B. Meyer, Christopher A. Haiman, Laurence Kolonel, Brian E. Henderson, Loı̈c Le Marchand, Paul Brennan, Suleeporn Sangrajrang, Valérie Gaborieau, Fabrice Odefrey, Chen‐Yang Shen, Pei‐Ei Wu, Hui‐Chun Wang, Diana Eccles, D. Gareth Evans, Julian Peto, Olivia Fletcher, Nichola Johnson, Sheila Seal, Michael R. Stratton, Nazneen Rahman, Georgia Chenevix‐Trench, Stig E. Bojesen, Børge G. Nordestgaard, C. K. Axelsson, Montserrat García‐Closas, Louise A. Brinton, Stephen J. Chanock, Jolanta Lissowska, Beata Pepłońska, Heli Nevanlinna, Rainer Fagerholm, Hannaleena Eerola, Daehee Kang, Keun-Young Yoo, Dong‐Young Noh, Sei Hyun Ahn, David J. Hunter, Susan E. Hankinson, David G. Cox, Per Hall, Sara Wedrén, Jianjun Liu, Yen-Ling Low, Natalia Bogdanova, Peter Schürmann, Thilo Dörk, Rob A.�E.�M. Tollenaar, Catharina E. Jacobi, Peter Devilee, Jan G.M. Klijn, Alice J. Sigurdson, Michele M. Doody, Bruce H. Alexander, Jinghui Zhang, Angela Cox, Ian W. Brock, Gordon R. Macpherson, Malcolm Reed, Fergus J. Couch, Ellen L. Goode, Janet E. Olson, Hanne Meijers‐Heijboer, Ans van den Ouweland, André G. Uitterlinden, Fernando Rivadeneira, Roger L. Milne, Glòria Ribas, Anna González‐Neira, Javier Benı́tez, John L. Hopper, Margaret McCredie, Melissa C. Southey, Graham G. Giles, Chris Schroen, Christina Justenhoven, Hiltrud Brauch, Ute Hamann +99 moreopenalex +3 more sourcesReplication of the Association of the 6q22.31c Locus near with Pulse Rate in the Korean Population [PDF]
Genomics & Informatics, 2012 Pulse rate is known to be related to diverse phenotypes, such as cardiovascular diseases, lifespan, arrhythmia, hypertension, lipids, diabetes, and menopause. We have reported two genomewide significant genetic loci responsible for the variation in pulse Nam Hee Kim, Young Jin Kim, Ji Hee Oh, Yoon Shin Cho +3 moredoaj +1 more sourceGenome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology
Nature Genetics, 2021 Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-wide association study of 41,917 bipolar disorder cases and 371,549 controls of European ancestry, which identified 64 associated genomic loci.N. Mullins, A. Forstner, K. O’Connell, B. Coombes, J. Coleman, Zhen Qiao, T. Als, T. Bigdeli, S. Børte, J. Bryois, A. Charney, O. K. Drange, M. Gandal, S. Hagenaars, M. Ikeda, Nolan Kamitaki, Minsoo Kim, Kristi Krebs, Georgia Panagiotaropoulou, B. Schilder, Laura G. Sloofman, S. Steinberg, V. Trubetskoy, B. Winsvold, H. Won, L. Abramova, K. Adorjan, E. Agerbo, M. A. Al Eissa, D. Albani, N. Alliey-Rodriguez, A. Anjorin, V. Antilla, A. Antoniou, S. Awasthi, J. Baek, Marie Bækvad-Hansen, N. Bass, M. Bauer, E. Beins, Sarah E. Bergen, A. Birner, C. Bøcker Pedersen, E. Bøen, M. Boks, R. Bosch, M. Brum, B. Brumpton, N. Brunkhorst-Kanaan, M. Budde, J. Bybjerg-Grauholm, W. Byerley, M. Cairns, M. Casas, P. Cervantes, Toni‐Kim Clarke, C. Cruceanu, A. Cuellar-Barboza, J. Cunningham, D. Curtis, P. Czerski, A. Dale, N. Dalkner, F. David, F. Degenhardt, S. Djurovic, Amanda Dobbyn, A. Douzenis, T. Elvsåshagen, V. Escott-Price, I. Ferrier, A. Fiorentino, T. Foroud, L. Forty, J. Frank, O. Frei, N. Freimer, L. Frisén, K. Gade, J. Garnham, J. Gelernter, Marianne Giørtz Pedersen, I. Gizer, S. Gordon, K. Gordon-Smith, T. Greenwood, J. Grove, J. Guzmán-Parra, Kyooseob Ha, M. Haraldsson, M. Hautzinger, U. Heilbronner, D. Hellgren, S. Herms, P. Hoffmann, P. Holmans, L. Huckins, S. Jamain, Jessica S. Johnson, J. Kalman, Y. Kamatani, J. Kennedy, S. Kittel-Schneider, J. Knowles, M. Kogevinas, M. Koromina, T. Kranz, H. Kranzler, M. Kubo, R. Kupka, S. Kushner, C. Lavebratt, J. Lawrence, M. Leber, Heon-Jeong Lee, Phil H. Lee, S. Levy, Catrin E Lewis, C. Liao, S. Lucae, M. Lundberg, D. Macintyre, S. Magnusson, W. Maier, A. Maihofer, D. Malaspina, E. Maratou, Lina Martinsson, M. Mattheisen, S. Mccarroll, N. McGregor, P. McGuffin, J. Mckay, H. Medeiros, S. Medland, V. Millischer, G. Montgomery, J. Moran, D. Morris, Thomas W. Mühleisen, N. O’Brien, C. O’Donovan, Loes M. Olde Loohuis, L. Oruč, S. Papiol, A. Pardiñas, A. Perry, A. Pfennig, E. Porichi, J. Potash, D. Quested, T. Raj, M. Rapaport, J. R. DePaulo, E. Regeer, J. Rice, F. Rivas, M. Rivera, Julian Roth, P. Roussos, D. Ruderfer, C. Sánchez-Mora, E. Schulte, F. Senner, S. Sharp, P. Shilling, E. Sigurdsson, L. Sirignano, C. Slaney, O. Smeland, Danny J. Smith, J. Sobell, Christine Søholm Hansen, M. Soler Artigas, A. Spijker, Dan J Stein, J. Strauss, B. Świątkowska, C. Terao, T. Thorgeirsson, Claudio Toma, P. Tooney, Evangelia Eirini Tsermpini, M. Vawter, H. Vedder, J. Walters, S. Witt, S. Xi, Wei Xu, J. Yang, A. Young, Hannah Young, P. Zandi, Hang Zhou, L. Zillich, R. Adolfsson, I. Agartz, M. Alda, L. Alfredsson, Gulja Babadjanova, L. Backlund, B. Baune, F. Bellivier, S. Bengesser, W. Berrettini, D. Blackwood, M. Boehnke, A. Børglum, G. Breen, V. Carr, S. Catts, A. Corvin, N. Craddock, U. Dannlowski, D. Dikeos, T. Esko, B. Étain, P. Ferentinos, M. Frye, J. Fullerton, M. Gawlik, E. Gershon, F. Goes, Melissa J. Green, M. Grigoroiu-Serbanescu, J. Hauser, F. Henskens, J. Hillert, K. Hong, D. Hougaard, C. Hultman, K. Hveem, N. Iwata, A. Jablensky, I. Jones, L. Jones, R. Kahn, J. Kelsoe, G. Kirov, M. Landén, M. Leboyer, C. Lewis, Qingqin S. Li, J. Lissowska, C. Lochner, C. Loughland, N. Martin, C. Mathews, F. Mayoral, S. McElroy, A. McIntosh, F. McMahon, I. Melle, P. Michie, L. Milani, P. Mitchell, G. Morken, O. Mors, P. Mortensen, B. Mowry, B. Müller-Myhsok, R. Myers, B. Neale, C. Nievergelt, M. Nordentoft, M. Nöthen, M. O’Donovan, K. Oedegaard, T. Olsson, M. Owen, S. Paciga, C. Pantelis, C. Pato, M. Pato, G. Patrinos, R. Perlis, D. Posthuma, J. Ramos-Quiroga, A. Reif, E. Reininghaus, M. Ribasés, M. Rietschel, S. Ripke, G. Rouleau, Takeo Saito, U. Schall, M. Schalling, P. Schofield, T. Schulze, L. Scott, R. Scott, A. Serretti, C. Shannon Weickert, J. Smoller, H. Stefánsson, K. Stefánsson, E. Stordal, F. Streit, P. Sullivan, G. Turecki, A. Vaaler, E. Vieta, J. Vincent, I. Waldman, T. Weickert, T. Werge, N. Wray, J. Zwart, J. Biernacka, J. Nurnberger, S. Cichon, H. Edenberg, E. Stahl, A. McQuillin, A. Di Florio, R. Ophoff, O. Andreassen +316 moresemanticscholar +1 more sourceHow data science and AI-based technologies impact genomics
Singapore Medical Journal, 2023 Advancements in high-throughput sequencing have yielded vast amounts of genomic data, which are studied using genome-wide association study (GWAS)/phenome-wide association study (PheWAS) methods to identify associations between the genotype and phenotype.Jing Lin, Kee Yuan Ngiamdoaj +1 more sourceThe genetics of obesity: A narrative review [PDF]
Precision and Future Medicine, 2022 Monogenic obesity is a rare, early-onset, and severe form of obesity that has a Mendelian inheritance pattern, high penetrance, and large genetic effect. In contrast, common polygenic obesity is more prevalent and has pattern of heritability derived from Young Bae Sohndoaj +1 more source
