Genome-wide association study gwas

Results 221 to 230 of about 188,567 (300)

Trajectories of genetic risk across dimensions of alcohol use behaviors

Addiction, EarlyView.
Abstract Background and aims Alcohol use behaviors (AUBs) manifest in a variety of normative and problematic ways across the life course, all of which are heritable. Twin studies show that genetic influences on AUBs change across development, but this is usually not considered in research identifying and investigating the genes linked to AUBs ...
Jeanne E. Savage +127 more
wiley +1 more source

Replication of genome-wide association study (GWAS) susceptibility loci in a Latino bipolar disorder cohort. [PDF]

Bipolar Disord, 2016
Gonzalez S +14 more
europepmc +1 more source

Bidirectional genetic and phenotypic links between smoking and striatal iron content involving dopaminergic and inflammatory pathways

Addiction, EarlyView.
Abstract Background and aims Tobacco smoking is a major risk factor for cardiovascular and lung diseases. A better understanding of its neurobiological underpinnings will benefit the prevention of smoking‐related illnesses and mortality. Previous studies link smoking to increased iron concentration in the striatum, a central component of the brain's ...
Olga Trofimova, Ilaria Iuliani, Sven Bergmann +2 more
wiley +1 more source

Exploring causal correlations between oily fish intake and multiple sclerosis: A two-sample Mendelian randomization study. [PDF]

Asia Pac J Clin Nutr
Chang S, Shi K, Zhang M.
europepmc +1 more source

From SNPs to pathways: Biological interpretation of type 2 diabetes (T2DM) genome wide association study (GWAS) results. [PDF]

PLoS One, 2018
Cirillo E +8 more
europepmc +1 more source

Mediation of Polygenic Asthma Risk Through Gene Expression

Allergy, EarlyView.
We apply published PRSs in African‐ancestry individuals and quantify the extent to which the PRS‐asthma relationship is mediated by clinical biomarkers and gene‐expression signatures of asthma. We found the best PRS to be the one derived using the largest sample size and including African‐ancestry individuals.
Rakesh Natarajan +29 more
wiley +1 more source

Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population. [PDF]

Nutrients, 2019
Coltell O +14 more
europepmc +1 more source

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits [PDF]

, 2017
Barata, Llilda +9 more
core +1 more source

Causal relationship between immune cells and idiopathic thrombocytopenic purpura: A bidirectional Mendelian randomization study

Rheumatology &Autoimmunity, EarlyView.
Heyi Zhang +9 more
wiley +1 more source

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh +7 more
wiley +1 more source

gwas
transcriptome-wide association study twas
genome-wide association study

genetics
genome wide association study gwas
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