Results 261 to 270 of about 3,743,554 (329)
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Benchmarking long-read variant calling in diploid and polyploid genomes: insights from human and plants. [PDF]
Fukasawa Y.
europepmc +1 more source
Evidence for integrated EBV genomes in Raji cellular DNA
Maria Anvret +2 more
openalex +2 more sources
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
ntSynt: multi-genome synteny detection using minimizer graph mappings. [PDF]
Coombe L +4 more
europepmc +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
<i>De Novo</i> Genome Assembly of the Myanmar Puddle Frog, <i>Phrynoglossus myanhessei</i> (Anura: Dicroglossidae). [PDF]
Geiß K, Köhler G, Janke A.
europepmc +1 more source

