Results 1 to 10 of about 2,597,842 (244)
Genome assembly composition of the String “ACGT” array: a review of data structure accuracy and performance challenges [PDF]
PeerJ Computer Science, 2023 Background The development of sequencing technology increases the number of genomes being sequenced. However, obtaining a quality genome sequence remains a challenge in genome assembly by assembling a massive number of short strings (reads) with the ...
Sherif Magdy Mohamed Abdelaziz Barakat +4 more
doaj +2 more sources
MitoHiFi: a python pipeline for mitochondrial genome assembly from PacBio high fidelity reads
bioRxiv, 2023 Background PacBio high fidelity (HiFi) sequencing reads are both long (15–20 kb) and highly accurate (> Q20). Because of these properties, they have revolutionised genome assembly leading to more accurate and contiguous genomes.
Marcela Uliano-Silva +9 more
semanticscholar +1 more source
Effects of GC bias in next-generation-sequencing data on de novo genome assembly. [PDF]
PLoS ONE, 2013 Next-generation-sequencing (NGS) has revolutionized the field of genome assembly because of its much higher data throughput and much lower cost compared with traditional Sanger sequencing. However, NGS poses new computational challenges to de novo genome
Yen-Chun Chen +4 more
doaj +1 more source
Horticulture Research, 2023 A high-quality genome is the basis for studies on functional, evolutionary, and comparative genomics. The majority of attention has been paid to the solution of complex chromosome structures and highly repetitive sequences, along with the emergence of a ...
Yunzhi Lin +14 more
semanticscholar +1 more source
Wellcome Open Research, 2021 We present a genome assembly from an individual male Rattus norvegicus (the Norway rat; Chordata; Mammalia; Rodentia; Muridae). The genome sequence is 2.44 gigabases in span. The majority of the assembly is scaffolded into 20 chromosomal pseudomolecules,
Kerstin Howe +20 more
doaj +1 more source
Time- and memory-efficient genome assembly with Raven
Nature Computational Science, 2021 Whole genome sequencing technologies are unable to invariably read DNA molecules intact, a shortcoming that assemblers try to resolve by stitching the obtained fragments back together.
Robert Vaser, M. Šikić
semanticscholar +1 more source
Genome Biology, 2022 Advancing crop genomics requires efficient genetic systems enabled by high-quality personalized genome assemblies. Here, we introduce RagTag, a toolset for automating assembly scaffolding and patching, and we establish chromosome-scale reference genomes ...
Michael Alonge +9 more
semanticscholar +1 more source
Optical maps refine the bread wheat Triticum aestivum cv. Chinese Spring genome assembly
The Plant Journal, 2021 Summary Until recently, achieving a reference‐quality genome sequence for bread wheat was long thought beyond the limits of genome sequencing and assembly technology, primarily due to the large genome size and > 80% repetitive sequence content.
Tingting Zhu +15 more
semanticscholar +1 more source
Wellcome Open Research, 2022 We present a genome assembly from an individual female Vespula germanica (the German wasp; Arthropoda; Insecta; Hymenoptera; Vespidae). The genome sequence is 206 megabases in span.
Liam M. Crowley
doaj +1 more source
Rapid genome mapping in nanochannel arrays for highly complete and accurate de novo sequence assembly of the complex Aegilops tauschii genome. [PDF]
PLoS ONE, 2013 Next-generation sequencing (NGS) technologies have enabled high-throughput and low-cost generation of sequence data; however, de novo genome assembly remains a great challenge, particularly for large genomes.
Alex R Hastie +12 more
doaj +1 more source