Results 111 to 120 of about 2,597,991 (390)
CGAL: computing genome assembly likelihoods [PDF]
Genome Biology, 2013 AbstractAssembly algorithms have been extensively benchmarked using simulated data so that results can be compared to ground truth. However, in de novo assembly, only crude metrics such as contig number and size are typically used to evaluate assembly quality. We present CGAL, a novel likelihood-based approach to assembly assessment in the absence of a
Rahman, Atif, Pachter, Lior
openaire +4 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
A high-quality chromosome-level genome assembly reveals genetics for important traits in eggplant
Horticulture Research, 2020 Eggplant (Solanum melongena L.) is an economically important vegetable crop in the Solanaceae family, with extensive diversity among landraces and close relatives.
Qingzhen Wei +5 more
semanticscholar +1 more source
novoBreak: local assembly for breakpoint detection in cancer genomes. [PDF]
, 2017 We present novoBreak, a genome-wide local assembly algorithm that discovers somatic and germline structural variation breakpoints in whole-genome sequencing data.
Boutros, Paul +10 more
core
LASER: Large genome ASsembly EvaluatoR [PDF]
BMC Research Notes, 2015 Genome assembly is a fundamental problem with multiple applications. Current technological limitations do not allow assembling of entire genomes and many programs have been designed to produce longer and more reliable contigs. Assessing the quality of these assemblies and comparing those produced by different tools is essential in choosing the best ...
Khiste, Nilesh, Ilie, Lucian
openaire +2 more sources
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
A chromosome-level genome assembly of the Korean minipig (Sus scrofa)
Scientific DataRecent advancements in sequencing and genome assembly technologies have led to rapid generation of high-quality genome assemblies for various species and breeds.
Suyeon Wy +5 more
doaj +1 more source
A new and improved genome sequence of Cannabis sativa
GigaByte, 2020 Cannabis is a diploid species (2n = 20), the estimated haploid genome sizes of the female and male plants using flow cytometry are 818 and 843 Mb respectively.
Shivraj Braich +3 more
doaj +1 more source
The Atlas Genome Assembly System [PDF]
Genome Research, 2004 Atlas is a suite of programs developed for assembly of genomes by a “combined approach” that uses DNA sequence reads from both BACs and whole-genome shotgun (WGS) libraries. The BAC clones afford advantages of localized assembly with reduced computational load, and provide a robust method for dealing with repeated sequences.
Paul, Havlak +7 more
openaire +2 more sources
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source