Results 11 to 20 of about 473,506 (307)
Molecular Biotechnology, 2022 Recent advances in genome editing technologies have redefined our ability to probe and precisely edit the human genome and epigenome in vitro and in vivo. More specifically, RNA-guided CRISPR/Cas systems have revolutionized the field due to their simplicity in design and adaptability across biological systems.
Maura McGrail +2 more
core +7 more sources
Genome editing in forest trees [PDF]
, 2023 Since the first CRISPR/Cas-mediated genome editing of poplar in 2015, an increasing number of tree species are being genome-edited. Although the availability of genome sequences, tissue culture and transformation systems are limiting factors, research is
Zahn, Virginia +3 more
core +1 more source
Genome Editing in Biotech Regulations Worldwide [PDF]
, 2023 Since the introduction of genome editing techniques in breeding and the first commercial products on the market, various governments or jurisdictions have attempted to clarify the legal classification of genome editing in relation to their genetic ...
Sprink, Thorben, Wilhelm, Ralf
core +1 more source
Genome editing for nutrient use efficiency in crops [PDF]
, 2022 Plant breeders have concentrated on increasing the yields, and in turn, the production in the last century to meet the increasing food demand, while ignoring the nutrition values of staple food crops.
Yavuz, Caner +4 more
core +1 more source
Addressing Cognitive Vulnerabilities Through Genome and Epigenome Editing: Techno-Legal Adaptations for Persons with Intellectual Disabilities [PDF]
, 2022 Special Issue: Gene Editing, Health Innovation, Regulation.Copyright © 2022 The Author. The key aim of this paper is to highlight the oft-under-represented narrative of how persons with disabilities (specifically, those with intellectual disabilities ...
Lau, PL
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Genome Editing for Mucopolysaccharidoses [PDF]
International Journal of Molecular Sciences, 2020 Genome editing holds the promise of one-off and potentially curative therapies for many patients with genetic diseases. This is especially true for patients affected by mucopolysaccharidoses as the disease pathophysiology is amenable to correction using multiple approaches. Ex vivo and in vivo genome editing platforms have been tested primarily on MSPI
Edina Poletto +2 more
openaire +2 more sources
Journal of Experimental Medicine, 2023 CRISPR/Cas9 genome editing techniques have the potential to treat previously untreatable inherited genetic disorders of vision by correcting mutations that cause these afflictions. Using a prime editor, Qin et al. (2023. J. Exp. Med.https://doi.org/10.1084/jem.20220776) restored visual functions in a mouse model (rd10) of retinitis pigmentosa.
Samuel W. Du, Krzysztof Palczewski
openaire +4 more sources
Prospects for Plant Genome Editing
, 2023 Genome editing – the focus of this book – is a set of methods that provide opportunities to precisely and efficiently improve crop traits by tailoring genes and regulatory domains.
Woźniak-Gientka, Ewa +5 more
core +1 more source
Transgene-Free Genome Editing in Plants
, 2022 Genome editing has revolutionized genetics and breeding likewise. Especially in plant breeding, it opened new ways to address traits with never known specificity.
Sprink, Thorben +2 more
core +1 more source
Genome Editing by Grafting. [PDF]
Int J Mol SciGrafting is the process of joining parts of two plants, allowing the exchange of molecules such as small RNAs (including microRNAs and small interfering RNAs), messenger RNAs, and proteins between the rootstock and the scion. Genome editing by grafting exploits RNAs, such as tRNA-like sequences (TLS motifs), to deliver the components (RNA) of the ...
Simoni S +3 more
europepmc +3 more sources