Results 221 to 230 of about 622,112 (341)

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Engineering and comparison of cas12a-based genome editing systems in plants. [PDF]

Plant J
Bircheneder M, Parniske M.
europepmc   +1 more source

Genome Editing Technologies: Historical Roots, Current Landscape, and Future Directions

Fatimah Alatiyyah, Hüseyin Tombuloğlu, Galyah Alhamid, Abdullah Alhamid, Roaa Zidan, Halbay Turumtay, Aysel Karagöz, Ali A. Rabaan   +7 more
openalex   +2 more sources

Highly Efficient, Rapid and Co-CRISPR-Independent Genome Editing in Caenorhabditis elegans [PDF]

, 2017
Harriet Prior, Ali K Jawad, Lauren MacConnachie, Asim A. Beg   +3 more
openalex   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Genome Editing

Oncology Times, 2017
openaire   +2 more sources

Floral stage optimization and immune evasion enhance Agrobacterium-mediated genome editing in Arabidopsis. [PDF]

New Phytol
Liu MS, Huang TK, Wang YC, Wang SC, Wu CH, Kuo CH, Lai EM.   +6 more
europepmc   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Chronic In Vivo CRISPR-Cas Genome Editing: Challenges, Long-Term Safety, and Outlook. [PDF]

Cells
Bao C, Channell CI, Tseng YH, Bailey J, Sbaiti N, Demirkol A, Tsang SH.   +6 more
europepmc   +1 more source

Genome editing strategies to generate working models of polycystic kidney disease [PDF]

Martina Migliorero, Donatella Marsalla, Francesco Edoardo Vallone, Alessandro Ragone, Claudia Saglia, Caterina Scolari, Valeria Bracciamà, Francesca Arruga, Monica Sorbini, Angelo Corso Faini, Licia Peruzzi, Tiziana Vaisitti, Silvia Deaglio   +12 more
openalex   +1 more source