Results 51 to 60 of about 526,413 (332)
Analog epigenetic memory revealed by targeted chromatin editing
Cell GenomicsSummary: Cells store information by means of chromatin modifications that persist through cell divisions and can hold gene expression silenced over generations.
Sebastian Palacios +7 more
doaj +1 more source
Modified Gene Editing Systems: Diverse Bioengineering Tools and Crop Improvement
Frontiers in Plant Science, 2022 Gene-editing systems have emerged as bioengineering tools in recent years. Classical gene-editing systems include zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and clustered regularly interspaced short ...
Guoning Zhu, Hongliang Zhu
doaj +1 more source
Approaches for bacteriophage genome engineering
Trends in Biotechnology, 2023 In recent years, bacteriophage research has been boosted by a rising interest in using phage therapy to treat antibiotic-resistant bacterial infections. In addition, there is a desire to use phages and their unique proteins for specific biocontrol applications and diagnostics.
Marina Mahler +4 more
openaire +2 more sources
Characterization of the complete chloroplast genome of Allium tuberosum
Mitochondrial DNA. Part B. Resources, 2019 Allium tuberosum is a popular vegetable, condiment, and even a traditional Chinese medicine. Here, the complete chloroplast genome sequence of Allium tuberosum was reported.
Hongxia Wang +5 more
doaj +1 more source
Bacteria herald a new era of gene editing. [PDF]
, 2013 The demonstration that nucleases guided by bacterial RNA can disrupt human genes represents a landmark in the rapidly developing field of genome ...
Segal, David J
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The GB4.0 Platform, an All-In-One Tool for CRISPR/Cas-Based Multiplex Genome Engineering in Plants
Frontiers in Plant Science, 2021 CRISPR/Cas ability to target several loci simultaneously (multiplexing) is a game-changer in plant breeding. Multiplexing not only accelerates trait pyramiding but also can unveil traits hidden by functional redundancy. Furthermore, multiplexing enhances
Marta Vazquez-Vilar +12 more
doaj +1 more source
Genome engineering technologies in rabbits
The Journal of Biomedical Research, 2021 The rabbit has been recognized as a valuable model in various biomedical and biological research fields because of its intermediate size and phylogenetic proximity to primates. However, the technology for precise genome manipulations in rabbit has been stalled for decades, severely limiting its applications in biomedical research.
Song, J +5 more
openaire +3 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Removal of a Subset of Non-essential Genes Fully Attenuates a Highly Virulent Mycoplasma Strain
Frontiers in Microbiology, 2019 Mycoplasmas are the smallest free-living organisms and cause a number of economically important diseases affecting humans, animals, insects, and plants.
Joerg Jores +22 more
doaj +1 more source