Results 61 to 70 of about 3,929,879 (390)
Induction of gametocytogenesis in human malaria parasites: from stress to genome editing
Frontiers in MicrobiologyGametocytogenesis is a crucial process in which malaria parasites transition from their asexual stage to the sexual-stage gametocytes. This transformation enables the parasite to infect and multiply within the Anopheles mosquito, the vector responsible ...
Rishitharan Subramaniam +4 more
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A Computational Method for the Rate Estimation of Evolutionary Transpositions
, 2015 Genome rearrangements are evolutionary events that shuffle genomic architectures. Most frequent genome rearrangements are reversals, translocations, fusions, and fissions.
J. Ma +8 more
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Developments in the tools and methodologies of synthetic biology. [PDF]
, 2014 Synthetic biology is principally concerned with the rational design and engineering of biologically based parts, devices, or systems. However, biological systems are generally complex and unpredictable, and are therefore, intrinsically difficult to ...
Freemont, P +3 more
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Precision genome editing in plants: state-of-the-art in CRISPR/Cas9-based genome engineering
BMC Plant Biology, 2020 Traditionally, generation of new plants with improved or desirable features has relied on laborious and time-consuming breeding techniques. Genome-editing technologies have led to a new era of genome engineering, enabling an effective, precise, and rapid
Naoki Wada +3 more
semanticscholar +1 more source
Pharmaceutics, 2020 DNA delivery is at the forefront of current research efforts in gene therapy and synthetic biology. Viral vectors have traditionally dominated the field; however, nonviral delivery systems are increasingly gaining traction.
Francesco Aulicino +2 more
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Molecular Therapy: Nucleic Acids, 2021 The utility of CRISPR-Cas9 to repair or reverse diseased states that arise from recent genetic mutations in the human genome is now widely appreciated. The use of CRISPR to “design” the outcomes of biology is challenged by both specialized ethicists and ...
Lais de Lima Balico, Eric A. Gaucher
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Analog epigenetic memory revealed by targeted chromatin editing
Cell GenomicsSummary: Cells store information by means of chromatin modifications that persist through cell divisions and can hold gene expression silenced over generations.
Sebastian Palacios +7 more
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Modified Gene Editing Systems: Diverse Bioengineering Tools and Crop Improvement
Frontiers in Plant Science, 2022 Gene-editing systems have emerged as bioengineering tools in recent years. Classical gene-editing systems include zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and clustered regularly interspaced short ...
Guoning Zhu, Hongliang Zhu
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Characterization of the complete chloroplast genome of Allium tuberosum
Mitochondrial DNA. Part B. Resources, 2019 Allium tuberosum is a popular vegetable, condiment, and even a traditional Chinese medicine. Here, the complete chloroplast genome sequence of Allium tuberosum was reported.
Hongxia Wang +5 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source