Results 201 to 210 of about 176,908 (324)

Genome mining of Bacillus thuringiensis strain SY49.1 reveals novel candidate pesticidal and bioactive compounds [PDF]

open access: hybrid
Semih Yılmaz   +5 more
openalex   +1 more source

Cellular Stress, Inflammation and Barrier Damage in Gut Epithelial Cells Caused by Aspartame

open access: yesAllergy, EarlyView.
This study shows that aspartame, at dietary‐relevant doses, induces cytotoxicity, cellular distress associated with endoplasmic reticulum stress, oxidative stress, DNA replication and repair mechanism disturbance culminating in epithelial barrier damage.
Yagiz Pat   +16 more
wiley   +1 more source

DysRegNet: Patient‐specific and confounder‐aware dysregulated network inference towards precision therapeutics

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Gene regulation is frequently altered in diseases in unique and patient‐specific ways. Hence, personalised strategies have been proposed to infer patient‐specific gene‐regulatory networks. However, existing methods do not scale well because they often require recomputing the entire network per sample.
Johannes Kersting   +5 more
wiley   +1 more source

Integrated genome mining and phytohormone profiling of six plant growth-promoting elite bacterial strains. [PDF]

open access: yesArch Microbiol
Ercole TG   +7 more
europepmc   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

open access: yesBritish Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi   +10 more
wiley   +1 more source

Genome Mining of Isoindolinone-Containing Peptide Natural Products. [PDF]

open access: yesJ Am Chem Soc
Zhang Y   +5 more
europepmc   +1 more source

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